HCTU CAS 330645-87-9 Peptide Coupling Reagent Maʻemaʻe >99.0% (HPLC) Hale Hana

ʻO ka HCTU (CAS: 330645-87-9) he mea hoʻohui hou i hoʻohana ʻia i ka wā o ke kaʻina hana o ka solid phase peptide synthesis (SPPS), e like me HBTU, i loaʻa i nā haʻawina hoʻohālikelike e hāʻawi i nā hopena kiʻekiʻe i ka TBTU i ka synthesis. o nā peptides paʻakikī, i nā hui hoʻopaʻa ʻia, a me nā cyclizations.He mea nui ka peptide synthesis i loko o ke kemika, e ʻae iā mākou e hana i nā peptides hou a me nā mea paʻa (ʻo ia ka iwi kuamoʻo o nā protein).
ʻO ka HCTU kahi mea hoʻohui hoʻohui maikaʻi loa i hiki ke hoʻohana ʻia ma ke ʻano he kumu kūʻai haʻahaʻa i nā mea hoʻopiʻi ʻoi aku ka maikaʻi a maikaʻi loa e like me HATU ke makemake ʻia nā manawa hoʻohui wikiwiki (5 min a i ʻole).Hoʻonui ka manawa hoʻohui wikiwiki i ka hoʻonui ʻana i ka huahana, a i kekahi mau mea hiki ke hopena i nā peptides crude maʻemaʻe ma ka ʻae ʻole ʻana i nā ʻaoʻao ʻaoʻao lohi e hoʻokūkū.
ʻO ka HCTU kahi reagent hoʻohui i hoʻohana ʻia no ka hoʻokumu ʻana o ka amide a me ka ester a hoʻohana mau ʻia i ka peptide synthesis.Ua like ka HCTU me HBTU a he mea pani kona Cl ma ke apo phenyl ma ke kulana 6.ʻAʻole ʻawaʻawa ʻo HCTU, paʻa i DMF, kūpono no ka pae paʻa a me ka synthesis solution.Hiki ke hoʻokō ʻia nā mea hoʻomaʻemaʻe kiʻekiʻe, nā manawa pane pōkole a me ka maikaʻi hoʻohui kiʻekiʻe ke hoʻohana ʻia ʻo HCTU, me nā hana e like me HATU akā ma ke kumu kūʻai aku.
ʻO ka HCTU kahi reagent no ka hoʻohui ʻana o ka pH activatable fluorescent probes kokoke-infrared a me ka β-amyloid kanaka e ke kemika Fmoc.ʻO HCTU kekahi mea hoʻoponopono no ka stereoselective Horner-Wadsworth-Emmons olefination, covalent ligation o nā peptides fluorescent i nā kiko quantum, a me ka alkylation o ke kaʻina telomere kanaka.