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N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Clean Clean
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate Maʻemaʻe Kiʻekiʻe

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate Maʻemaʻe Kiʻekiʻe

ʻO ka wehewehe pōkole:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8

Nānā: Melemele a ʻaneʻane Melemele Pada

Maʻemaʻe: ≥98.0% (HPLC)

ʻO Intermediate o Imatinib Mesylate (CAS: 220127-57-1) i ka mālama ʻana iā Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph+CML)

Kūlana Kiʻekiʻe, Hana Kūʻai

Inquiry: alvin@ruifuchem.com


Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

Hoʻolako Kalepa ʻo Imatinib Mesylate a me nā mea e pili ana i waena:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]ʻakika benzoic dihydrochloride CAS: 106261-49-8

Na Waiwai Kemika:

Inoa Kimia N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Nā huaʻōlelo like Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Helu CAS 152460-09-8
Helu CAT RF-PI228
Kūlana Kūʻai Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona
ʻĀpana Molekala C16H13N5O2
Kaumaha Molecular 307.31
Lae hehee 188.0~193.0 ℃
Brand ʻO Ruifu Chemical

Nā kikoʻī:

'ikamu Nā kikoʻī
Ka nana aku Melemele a ʻaneʻane Melemele Pada
Maemae ≥98.0% (HPLC)
Māmā (KF) ≤0.50%
Huina paumaele ≤2.0%
ʻO ka haumia hoʻokahi kiʻekiʻe ≤1.0%
Ke koena ma ka ʻā ≤0.50%
Metala Kaumaha ≤20ppm
Kūlana hoʻāʻo ʻOihana Kūlana
Hoʻohana Ka waena o Imatinib Mesylate (CAS: 220127-57-1)

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.

Pono:

1

FAQ:

Noi:

ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o N-(2-Methyl-5-nitrophenyl) -4-(pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) me ke kūlana kiʻekiʻe.He mea waena maʻamau i ka synthesis o Imatinib Mesylate (CAS: 220127-57-1).
ʻO ka Imatinib Mesylate kahi mole liʻiliʻi e kāohi ana i ka c-Abl protein-tyrosine kinase, kikoʻī loa no BCR-ABL, ka enzyme pili i ka maʻi maʻi myelogenous maʻi (CML) a me kekahi mau ʻano o ka maʻi leukemia lymphoblastic acute (ALL).ʻO kahi hanana translocation ma waena o nā chromosomes 9 a me 22 e hoʻopuka i ka chromosome Philadelphia, a laila e hoʻopuka i ka protein hui Bcr-Abl me ka hana kinase aberrant e hoʻoikaika i ka hoʻonui wikiwiki ʻana o ke kelepona.Hoʻopili ʻo Imatinib Mesylate i kēia kinase koʻikoʻi, hoʻopau i ka ulu pili CML.Ua hōʻike hou ʻia ʻo Imatinib Mesylate e kāohi i ka PDGFR a me nā tyrosine kinases e pili ana me c-Kit.Ua hoʻohana ʻia nā ʻano hana i loaʻa i ka Imatinib Mesylate i ka mālama ʻana i nā maʻi maʻi like ʻole.

E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou