Indapamide CAS 26807-65-8 Maʻemaʻe ≥99.5% (HPLC) API EP Hale Hana Kūlana Kiʻekiʻe
ʻO Shanghai Ruifu Chemical Co., Ltd. ʻo ia ka mea hana alakaʻi a me ka mea hoʻolako o Indapamide a me nā mea pili pili me ke ʻano kiʻekiʻe.
Indapamide CAS 26807-65-8
2-Methylindoline CAS 6872-06-6
1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
Inoa Kimia | Indapamide |
Nā huaʻōlelo like | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
Helu CAS | 26807-65-8 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C16H16ClN3O3S |
Kaumaha Molecular | 365.83 |
Lae hehee | 160.0~162.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a ʻaneʻane keʻokeʻo Crystalline pauda |
Ka hikiwawe | ʻAʻole hiki ke hoʻoheheʻe ʻia i ka wai;Hiki ke hoʻoheheʻe ʻia i loko o ka Ethanol |
ʻIkepili A | ʻO ka Ultraviolet a me ka ʻike ʻia ʻana o ka hoʻoheheʻe ʻana Spectrophotometry |
ʻIkepili B | Spectrophotometry hoʻomoʻa ʻana i ka infrared |
ʻIkepili C | Kromatography ʻōniʻoniʻo |
ʻO ka hoʻololi ʻana | -0.80°~ +0.80° (C=5, C2H5OH) |
Wai (EP 2.5.12) | <3.00% |
Lehu Sulphated (EP 2.4.14) | <0.10% |
Metala Kaumaha (EP 2.4.8) | <10ppm |
Na mea pili | |
haumia B | <0.30% |
Ka haumia ʻole i hōʻike ʻia | <0.10% |
Huina paumaele | <0.50% |
Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC) |
Kūlana hoʻāʻo | EP Kūlana |
Hoʻohana | API;ʻO kahi antihypertensive a me kahi diuretic |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO ka Indapamide (CAS: 26807-65-8) kahi lāʻau antihypertensive a me kahi diuretic.Ma ke kāohi ʻana i ka reabsorption o Na+ ma ka hope kokoke o nā tubules conflexion distal, hana ia i ka hopena diuretic a hoʻopaʻa pū i ka hoʻokomo ʻana o Ca2+.Loaʻa iā ia kahi koho kiʻekiʻe i ka ʻiʻo maʻemaʻe vascular, hoʻonui i nā moku liʻiliʻi peripheral a hana i ka hopena hypotensive.Akā ʻoi aku ka ikaika o ka hopena diuretic ma lalo o ka diuretic doses, ʻoi aku ka nui o ka hopena diuretic, akā ʻaʻohe thiazide diuretic hemahema, ʻaʻole ia he kumu o ka orthostatic hypotension, flush a reflective tachycardia, ma ke kiʻi koko, metabolism o ke koko. ʻAʻohe hopena o ka momona, ke kō a me ka renal, ʻaʻohe hopena maikaʻi o ka puʻuwai puʻuwai, ka puka ʻana o ka naʻau, ʻaʻohe hoʻololi nui i ka electrocardiogram (ecg) ʻaʻole ʻaʻohe hopena ʻike ʻia i ka ʻōnaehana pūpū a me ke aʻalolo autonomic.ʻO ka lawelawe waha o 2 ~ 3 chemicalbook H i hana i kahi hopena hypotensive, i mālama ʻia no 24h.ʻIke ʻia ka hopena diuretic ma 3h a hiki i kona hopena kiʻekiʻe loa ma 4 ~ 6h.He kūpono ʻo Indapamide no ka haʻahaʻa haʻahaʻa a me ka haʻahaʻa haʻahaʻa, hiki ke hoʻohana ʻia no ka puʻuwai congestive ma muli o ka paʻa ʻana o ka sodium wai, me ka hana ʻole o ka renal e pili pū ana i nā mea maʻi me ke koko kiʻekiʻe, diabetes, hyperlipidemia, hoʻohana i ka hopena antihypertensive he mea kupaianaha.