ʻO Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Maʻemaʻe >99.0% (HPLC) Hale Hana
ʻO Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan ʻaoʻao Chain Hydrochloride CAS 151257-01-1
Inoa Kimia | 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride |
Nā huaʻōlelo like | Irbesartan ʻaoʻao Chain Hydrochloride;Irbesartan Lactam haumia;Irbesartan haumia A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-one Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]non-1-en-4-one HCl |
Helu CAS | 151257-01-1 |
Helu CAT | RF-PI1894 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C11H18N2O·HCl |
Kaumaha Molecular | 230.74 |
Solubility i ka wai | Hiki i ka wai |
Lae hehee | 235.0~240.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keokeo a aneane keokeo Crystalline pauda |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) |
Nalo ma ka maloo | <0.50% |
Koena ma ka Ignition | <0.20% |
Huina paumaele | <1.00% |
Proton NMR Spectrum | Kūlike i ka hoʻolālā |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o Irbesartan (CAS: 138402-11-6) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride (CAS: 151257-01-1), i ʻike ʻia ʻo Irbesartan Side Chain Hydrochloride, he Intermediate o Irbesartan (Avapro) (CAS : 138402-11-6).ʻO Irbesartan kahi mea hoʻopaʻa i ka angiotensin II, ua hoʻokaʻawale ʻia nā mea hoʻokipa angiotensin II i AT1, AT2, hiki i ka irbesartan ke kāohi i ka AngⅠtransform i AngII ma ke koho ʻana i ka AT1 receptor o AngII, e kūʻē i ka angiotensin converting enzyme 1 receptor (AT1), ʻo ka antagonism o AT1 he 8500. mau manawa ma mua o ka AT2, hiki iā ia ke kāohi i ka vasoconstriction a me ka hoʻokuʻu ʻana o ka aldosterone ma ke koho ʻana i ka AngII paʻa me AT1 receptor a hopena i ka hopena antihypertensive.ʻAʻole ʻae kēia huahana i ka angiotensin hoʻololi i ka enzyme (ACE), renin, a me nā mea hoʻokipa hormone ʻē aʻe, ʻaʻole hoʻi e kāohi i ka hoʻoponopono ʻana i ke koko a me ke koena o nā kaila sodium ion.Hiki i ka Irbesartan ke hōʻemi i ka hoʻoponopono hou ʻana o ka myocardium, no laila e hōʻemi i ka nui o ka make o nā mea maʻi me ka hypertension, ʻo ia ka lāʻau lapaʻau maikaʻi loa no ka mālama ʻana i ka hypertension a me ka maʻi cardiovascular.