Ivabradine Hydrochloride CAS 148849-67-6 Maʻemaʻe >99.5% (HPLC) API Hale Hana
ʻO Ruifu Chemical Supply Ivabradine Hydrochloride Intermediates Me ka Maʻemaʻe Kiʻekiʻe
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Inoa Kimia | ʻO Ivabradine Hydrochloride |
Nā huaʻōlelo like | Ivabradine HCl |
Helu CAS | 148849-67-6 |
Helu CAT | RF-PI1812 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C27H36N2O5·HCl |
Kaumaha Molecular | 505.05 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIkepili | Hoʻokō ka HPLC/UV |
Maʻemaʻe / Kaʻina Hanana | >99.5% |
Nalo ma ka maloo | <1.00% (Hoʻomaloʻo iā ia ma 105 ℃ i loko o kahi mea maloʻo ea uila a hiki i ke kaumaha mau) |
Māmā | <1.00% |
Koena ma ka Ignition | <0.20% |
Max Hoʻokahi haumia | <0.50% |
Huina paumaele | <0.50% |
Isomer Optical | <0.50% |
Hoʻāʻo | >99.5% |
Nā Metala Kaumaha | <20ppm |
Hoʻololi kikoʻī | +6.5° ~ +8.5° (ma ke kumu maloʻo, 1% solution ma DMSO) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
Ivabradine Hydrochloride (CAS: 148849-67-6),I ka ho'āʻo ʻana e hoʻomohala i nā mea hana angina me ka ʻole o ka inotropic maikaʻi ʻole a me nā hopena hypotensive e pili ana me nā b-adrenergic blockers a me ka calcium channel blockers, ua ʻimi ʻia kahi papa hou o ka puʻuwai hoʻohaʻahaʻa puʻuwai e hana pono i ka node sinoatrial (SA).Hoʻopili pololei kēia mau mea hana bradycardic me ka cell pacemaking o ka node SA a me ka hyperpolarization- activated Inā ʻo ka pacemaking mua.Ua ulu aʻe ʻo Ivabradine ma ke ʻano he mea hoʻopaneʻe kikoʻī o If i kēia manawa ma o kona hoʻopili ʻana me nā f-channels ma ka ʻaoʻao intracellular o ka membrane plasma.ʻO ka hopena, hoʻemi ʻo Ivabradine i ka wikiwiki o ka depolarization diastolic a hoʻemi i ka puʻuwai puʻuwai.Ua ʻae ʻia no ka mālama ʻana i ka angina stable maʻamau a hāʻawi i kahi koho kūpono i nā poʻe maʻi me ka contraindication a i ʻole intolerance o nā b-blockers.Ke hoʻomaka nei ka loiloi no ka mālama ʻana i ka maʻi naʻau ischemic.