Lenvatinib Mesylate Intermediate CAS 15568-85-1 Maʻemaʻe >97.0% (HPLC) Hale Hana
ʻO Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Me ka Maʻemaʻe Kiʻekiʻe
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Inoa Kimia | 5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione |
Nā huaʻōlelo like | 5-(Methoxymethylene) Kaʻakika Meldrum;ʻO ka haumia ʻo Cabozantinib 56;Lenvatinib haumia 79 |
Helu CAS | 15568-85-1 |
Helu CAT | RF-PI1967 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C8H10O5 |
Kaumaha Molecular | 186.16 |
Lae hehee | 132.0~134.0 ℃ |
ʻO ka mānoanoa | 1.297±0.06 g/cm3 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda Melemele |
1 H NMR Spectrum | Kūlike me ka hoʻolālā |
Maʻemaʻe / Kaʻina Hanana | >97.0% (HPLC) |
Huina paumaele | <3.00% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Waena o Lenvatinib Mesylate (CAS: 857890-39-2) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
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ʻO 5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS:15568-85-1) he mea waena o Lenvatinib Mesylate (CAS: 857890-39-2).ʻO Lenvatinib kahi lāʻau maʻi maʻi thyroid i hoʻomohala ʻia e Eisai Corporation o Iapana (Code: E7080), nona ka mea paʻa o ka waha multi-receptor tyrosine kinase (RTK) a hiki ke kāohi i ka hana kinase o ka vascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), a me VEGFR3 (FLT4).Hiki nō hoʻi iā Lenvatinib ke kāohi i ke komo ʻana o nā RTK ʻē aʻe i ka angiogenesis pathological, ka ulu ʻana o ka maʻi maʻi, a me ka piʻi ʻana o ka maʻi maʻi koe wale nō kā lākou mau hana kelepona maʻamau me ka fibroblast growth factor (FGF) receptors FGFR1, 2, 3, a me 4;ʻO ka platelet-derived growth factor receptor (PDGFR [alpha]), KIT, a me RET.[Nā hōʻike]: He kūpono ʻo Lenvatinib no ka mālama ʻana i nā maʻi o ka maʻi maʻi thyroid o ka hoʻi hou ʻana a i ʻole ke ʻano metastasis, ke ʻano holomua a me ka radioactive iodine-refractory differentiated type.Ma Pepeluali 13, 2015, ua ʻae ka US FDA i ka lāʻau anticancer Lenvatinib no ka mālama ʻana i ka maʻi maʻi thyroid.ʻO Lenvatinib kahi mea hoʻopaneʻe enzyme multi-target, hiki iā ia ke pale i ka VEGFR2 a me VEGFR3 (vascular endothelial growth factor receptor).ʻO Lenvima ka inoa kālepa o Lenvatinib.Ma Mei 20, 2015, ua ʻae ka European Medicines Agency (EMA) iā Lenvatinib no ka mālama ʻana i ka invasive, locally advanced or metastatic differentiated (papillary, follicular, Hurthle type) thyroid cancer (DTC).I ka hoʻokolokolo ʻana, ʻo ka manawa ola median no nā maʻi o ka radioactive iodine-refractory DTC i mālama ʻia me Lenvatinib he 18 mau mahina aʻo ka waiwai no nā maʻi e lawe i ka placebo he 3 mahina wale nō.
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Lenvatinib Mesylate Intermediate CAS 15568-85-1...
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Lenvatinib Mesylate CAS 857890-39-2 Hōʻike 98.0~...
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Desquinolinyl Lenvatinib CAS 796848-79-8 Maʻemaʻe...
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4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatini...
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4-Amino-3-Chlorophenol Hydrochloride CAS 52671-...
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4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 4...
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Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8...
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Lenvatinib Mesylate Intermediate CAS 205448-65-...
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Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylat...