Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II Mea Kiʻekiʻe
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Letrozole
CAS: 112809-51-5
Aromatase Inhibitor II
API Kūlana Kiʻekiʻe, Hana Hana Kūʻai
| Inoa Kimia | Letrozole |
| Nā huaʻōlelo like | CGS-20267;Femara |
| Helu CAS | 112809-51-5 |
| Helu CAT | RF-API86 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
| ʻĀpana Molekala | C17H11N5 |
| Kaumaha Molecular | 285.3 |
| Lae hehee | 181.0 a i 183.0 ℃ |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
| Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o ka Dichloromethane, hiki ke hoʻoheheʻe ʻia i loko o ka Ethanol a ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai. |
| ʻIkepili IR | Kūlike ke kiko o ka hāpana me ka maʻamau kuhikuhi |
| ʻIke HPLC | ʻO ka manawa paʻa o ka hāpana hoʻāʻo e pili ana i ka maʻamau kuhikuhi |
| Waiwai (na KF) | ≤0.30% |
| Koena ma ka Ignition | ≤0.10% |
| Na mea pili | |
| Nā mea pili A | ≤0.30% |
| Nā mea pili B | ≤0.20% |
| ʻO nā mea haumia ʻole i hōʻike ʻia | ≤0.10% |
| Huina paumaele i hoakaka ole ia | ≤0.30% |
| Huina paumaele | ≤0.50% |
| Nā mea hoʻoheheʻe koena | |
| Ethyl Acetate | ≤0.50% |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| DMF | ≤0.088% |
| Nā Metala Kaumaha | ≤10ppm |
| Hoʻāʻo | 98.0%~102.0% (ma ke kumu anhydrous) |
| Ola Pahu | 24 mahina |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | API, Aromatase Inhibitor II |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Letrozole (CAS 112809-51-5) kahi ʻāpana o ka hanauna hou o nā mea hoʻopaneʻe aromatase koho nui a he mea hoʻoheheʻe benzotriazole i hana ʻia.Kāohi ʻo Letrozole i ka aromatase e hoʻohaʻahaʻa i nā pae estrogen, no laila e pale ai i ka estrogen mai ka hoʻoulu ʻana i ka ulu ulu.ʻO kāna hana in vivo he 150-250 mau manawa ʻoi aku ka ikaika ma mua o ka hanauna mua o ka aromatase inhibitor Amarante.No ka mea he koho nui loa ia, ʻaʻole ia e hoʻopili i nā hana glucocorticoid, mineralocorticoid a me thyroid;ʻoiai ma nā ʻano kiʻekiʻe, ʻaʻole e loaʻa nā hopena inhibiting i ka huna ʻana o ka corticosteroid adrenal, e hāʻawi ana iā ia i kahi kuhikuhi lapaʻau kiʻekiʻe.ʻAʻohe mea ʻawaʻawa huna o Letrozole i nā ʻōnaehana kino a me nā ʻāpana i hoʻopaʻa ʻia, ʻaʻohe mutagenicity a me nā hopena carcinogenic, ʻaʻohe liʻiliʻi o nā hopena ʻawaʻawa, ʻae maikaʻi ʻia, a ʻoi aku ka ikaika o nā hopena anticancer ma mua o nā mea paʻa aromatase a me nā lāʻau antiestrogen.He kūpono ʻo Letrozole no nā poʻe maʻi maʻi maʻi maʻi maʻi maʻi postmenopausal i pane ʻole i ka mālama ʻana i ka estrogen-suppressing a no ka mālama ʻana i ka maʻi maʻi umauma mua.Hoʻohana ʻia ia e mālama i nā poʻe maʻi postmenopausal me ka maʻi maʻi umauma kiʻekiʻe a lawelawe ʻo ia ma ke ʻano he lāʻau lapaʻau lua e hahai i ka mālama antiestrogen kūleʻa ʻole.
