Linagliptin CAS 668270-12-0 Maʻemaʻe ≥99.0% (HPLC) Hale Hana
Mea Manufacturer Supply, High Purity, Commercial Production
Inoa Kemika: Linagliptin
CAS: 668270-12-0
Inoa Kimia | Linagliptin |
Nā huaʻōlelo like | BI-1356;8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H -purine-2,6-dione |
Helu CAS | 668270-12-0 |
Helu CAT | RF-API105 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C25H28N8O2 |
Kaumaha Molecular | 472.54 |
Lae hehee | 197.0 a 200.0 ℃ |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia ma DMSO |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ʻole ke keʻokeʻo Crystalline pauda |
NMR | Kūlike me ka hoʻolālā |
Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha | ≤10ppm |
Na mea pili | |
Hoʻokahi haumia | ≤0.50% |
Huina paumaele | ≤1.0% |
Isomer | ≤0.15% |
Nā mea hoʻoheheʻe koena | |
Methanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO Linagliptin (CAS: 668270-12-0) kahi mea pale DPP-4 i hoʻomohala ʻia e Boehringer Ingelheim no ka mālama ʻana i ka maʻi diabetes type II.ʻElua mau hiʻohiʻona pharmacological e hoʻokaʻawale i ka linagliptin mai nā mea paʻa DPP-4 ʻē aʻe, ʻo ia ka loaʻa ʻana o ka pharmacokinetic profile non-linear a ʻaʻole i hoʻopau mua ʻia e ka ʻōnaehana renal.Ua ʻae ʻia ʻo Linagliptin (hoʻokahi lā i kēlā me kēia lā) e ka US FDA ma 2 Mei 2011 no ka mālama ʻana i ka maʻi diabetes type II.Ke kūʻai ʻia nei e Boehringer Ingelheim a me Lilly.Linagliptin, kūʻai ʻia ma lalo o ka inoa inoa ʻo Tradjenta ma waena o nā mea ʻē aʻe.Hoʻohana pū ʻia me ka hoʻoikaika kino a me ka ʻai.