3,3′,5-Triiodo-L-Thyronine (Liothyronine; T3) CAS 6893-02-3 Ma'ema'e >95.0% (HPLC) Hale Hana

3,3',5-Triiodo-L-Thyronine (Liothyronine; T3) (CAS: 6893-02-3) he potent thyroid hormone receptors TRα a me TRβ agonist me Kis o 2.33 nM no ka hTRα a me ka hTRβ.ʻO Liothyronine kahi hormone i huna ʻia e ka thyroid.Hoʻokumu ʻia ia e ka condensation o L-3-Monoiodotyrosine a me L-3.5-Diiodotyrosine.ʻOi aku ka liʻiliʻi o ka ʻiʻo thyroid a me ke koko ma mua o ka thyroxine, akā ʻo kāna hana olaola he 5 a 10 mau manawa kiʻekiʻe ma mua o ia.Loaʻa iā T3 ka hopena o ka hoʻoikaika ʻana i ka metabolism a me ka hoʻokuʻu ʻana i ka ikehu;hiki ke hoʻoikaika i ka ulu a me ka ulu ʻana.ʻO ka thyroid makua maʻamau e hūnā i ka 30 μg T3 i kēlā me kēia lā, 20% o T3 i loko o ka plasma mai ka huna pololei o ka thyroid, a ʻo 80% mai ka hoʻololi ʻana o ka plasma T4 ma ka ʻaoʻao.ʻO Levothyroxine a i ʻole L-Thyroxine he hormone thyroid synthetic i like kemika me thyroxine (T4), i hūnā maoli ʻia e nā follicular cell o ka thyroid gland.Hoʻohana ʻia e mālama i ka hemahema o ka hormone thyroid, a i kekahi manawa e pale i ka hoʻi hou ʻana o ka maʻi maʻi thyroid.E like me kona hoa huna maoli, ʻo ka levothyroxine kahi hui chiral i ka L-form.Ua hoʻohana ʻia ka lāʻau lapaʻau pili ʻo dextrothyroxine (D-thyroxine) i ka wā ma mua ma ke ʻano he lapaʻau no ka hypercholesterolemia (ke kiʻekiʻe o ka cholesterol kiʻekiʻe) akā ua hoʻihoʻi ʻia ma muli o nā hopena ʻaoʻao cardiac.Liothyroninehoʻohana maʻamau i ka wā o ka ʻokiʻoki, ka ʻai ʻai ʻana, a/a i ʻole ma mua o ka hoʻokūkū o ka hoʻomaʻamaʻa ʻana ma muli o ka pahuhopu honua o kēia mau māhele e wāwahi i ka momona o ke kino, ʻoiai i nā makahiki i hala iho nei ua loaʻa i ka T3 kekahi mea kaulana ma ke ʻano he mea pono i ka wā o ka bulking a me ka loaʻa ʻana o ka nui. o ka hoʻomaʻamaʻa ʻana (e hui pū me nā steroids) i mea e hoʻomaʻamaʻa maikaʻi ai i nā meaʻai a / a i ʻole e mālama i nā pae momona o ke kino i ka wā o ka nui o ka caloric intake.Hoʻohana maʻamau ʻia ʻo Liothyronine me nā steroid ma muli o kona hopena koʻikoʻi i ka metabolism o ke kino holoʻokoʻa.He mea nui ka hoʻomaopopo ʻana ʻaʻole i koho ʻole ʻia ʻo T3 i kāna mau waiwai e hoʻonui ai i ka metabolism - e hoʻonui like ia i ka metabolism o nā momona, nā haʻahaʻa, a me ka protein.No laila, ma waho aʻe o ka nui o ka T3, aia ka piʻi aʻe o ka nalo ʻana o ka ʻiʻo ma o ka hoʻonui ʻia ʻana o ka protein.Ma o ka hoʻohana ʻana i nā steroids a me kahi meaʻai i hoʻoponopono pono ʻia, hiki ke pale ʻia kēia nalowale ʻana o ka ʻiʻo ma muli o ka T3 ma muli o ka mālama ʻana i ka nitrogen a me nā waiwai mālama i ka protein o nā steroids.Hoʻohui pinepine ʻia ʻo Liothyronine me nā mea momona momona ʻē aʻe i mea e hoʻonui ai i kona hopena holoʻokoʻa, no ka mea e hana like ʻo ia me nā mea momona momona ʻē aʻe.