Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Maʻemaʻe >98.0% (GC) Lenvatinib Mesylate Intermediate Factory

ʻO ka wehewehe pōkole:

Inoa Kemika: Methyl 4-Amino-2-Methoxybenzoate

CAS: 27492-84-8

Maʻemaʻe: >98.0% (GC)

ʻAno: Keʻokeʻo a i ʻole ka pauka keʻokeʻo a i ʻole nā kristal

Kūwaena o Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Me ka Maʻemaʻe Kiʻekiʻe
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Na Waiwai Kemika:

Inoa Kimia	Methyl 4-Amino-2-Methoxybenzoate
Nā huaʻōlelo like	4-Amino-2-Methoxybenzoic Acid Methyl Ester;Methyl 4-Amino-o-Anisate;4-Amino-o-Anisic Acid Methyl Ester
Helu CAS	27492-84-8
Helu CAT	RF-PI1974
Kūlana Kūʻai	Ma ka waihona, hoʻonui ʻia a hiki i nā tona
ʻĀpana Molekala	C9H11NO3
Kaumaha Molecular	181.19
ʻO ka mānoanoa	1.179±0.060 g/cm3
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	ʻO ke keʻokeʻo i ka pauka keʻokeʻo a i ʻole nā aniani
Maʻemaʻe / Kaʻina Hanana	>98.0% (GC)
Maʻemaʻe / Kaʻina Hanana	97.5~102.5 (Nānā Nonaqueous)
Lae hehee	157.0~161.0 ℃
Nalo ma ka maloo	<1.00%
Huina paumaele	<2.0%
Infrared Spectrum	Kūlike i ka hoʻolālā
Proton NMR Spectrum	Kūlike i ka hoʻolālā
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	Waena o Lenvatinib Mesylate (CAS: 857890-39-2)

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

Hiki ke hoʻohana ʻia ka Methyl 4-Amino-2-Methoxybenzoate (CAS: 27492-84-8) ma ke ʻano he waena o Lenvatinib Mesylate (CAS: 857890-39-2).ʻO Lenvatinib kahi lāʻau maʻi maʻi thyroid i hoʻomohala ʻia e Eisai Corporation o Iapana (Code: E7080), nona ka mea paʻa o ka waha multi-receptor tyrosine kinase (RTK) a hiki ke kāohi i ka hana kinase o ka vascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), a me VEGFR3 (FLT4).Hiki nō hoʻi iā Lenvatinib ke kāohi i ke komo ʻana o nā RTK ʻē aʻe i ka angiogenesis pathological, ka ulu ʻana o ka maʻi maʻi, a me ka piʻi ʻana o ka maʻi maʻi koe wale nō kā lākou mau hana kelepona maʻamau me ka fibroblast growth factor (FGF) receptors FGFR1, 2, 3, a me 4;ʻO ka platelet-derived growth factor receptor (PDGFR [alpha]), KIT, a me RET.[Nā hōʻike]: He kūpono ʻo Lenvatinib no ka mālama ʻana i nā maʻi o ka maʻi maʻi thyroid o ka hoʻi hou ʻana a i ʻole ke ʻano metastasis, ke ʻano holomua a me ka radioactive iodine-refractory differentiated type.Ma Pepeluali 13, 2015, ua ʻae ka US FDA i ka lāʻau anticancer Lenvatinib no ka mālama ʻana i ka maʻi maʻi thyroid.ʻO Lenvatinib kahi mea hoʻopaneʻe enzyme multi-target, hiki iā ia ke pale i ka VEGFR2 a me VEGFR3 (vascular endothelial growth factor receptor).ʻO Lenvima ka inoa kālepa o Lenvatinib.Ma Mei 20, 2015, ua ʻae ka European Medicines Agency (EMA) iā Lenvatinib no ka mālama ʻana i ka invasive, locally advanced or metastatic differentiated (papillary, follicular, Hurthle type) thyroid cancer (DTC).I ka hoʻokolokolo ʻana, ʻo ka manawa ola median no nā maʻi o ka radioactive iodine-refractory DTC i mālama ʻia me Lenvatinib he 18 mau mahina aʻo ka waiwai no nā maʻi e lawe i ka placebo he 3 mahina wale nō.