Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Maʻemaʻe >98.0% (HPLC) Lenvatinib Mesylate Intermediate Factory
ʻO Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Me ka Maʻemaʻe Kiʻekiʻe
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Inoa Kimia | Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
Nā huaʻōlelo like | Lenvatinib haumia 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;Lenvaint-D |
Helu CAS | 205448-66-4 |
Helu CAT | RF-PI1970 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C12H10ClNO3 |
Kaumaha Molecular | 251.67 |
Lae paila | 377.4±37.0 ℃ |
ʻO ka mānoanoa | 1.320±0.06 g/cm3 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pau-keokeo a Melemele Paa Paa |
1 H NMR Spectrum | Kūlike me ka hoʻolālā |
Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) |
Nalo ma ka maloo | <1.00% |
Huina paumaele | <2.00% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena/Hoʻomaemae o Lenvatinib Mesylate (CAS: 857890-39-2) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) kahi mea waena o Lenvatinib Mesylate (CAS: 857890-39-2).ʻO Lenvatinib kahi lāʻau maʻi maʻi thyroid i hoʻomohala ʻia e Eisai Corporation o Iapana (Code: E7080), nona ka mea paʻa o ka waha multi-receptor tyrosine kinase (RTK) a hiki ke kāohi i ka hana kinase o ka vascular endothelial growth factor Receptors R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Hiki nō hoʻi iā Lenvatinib ke kāohi i ke komo ʻana o nā RTK ʻē aʻe i ka angiogenesis pathological, ka ulu ʻana o ka maʻi maʻi, a me ka piʻi ʻana o ka maʻi maʻi koe wale nō kā lākou mau hana kelepona maʻamau me ka fibroblast growth factor (FGF) receptors FGFR1, 2, 3, a me 4;ʻO ka platelet-derived growth factor receptor (PDGFR [alpha]), KIT, a me RET.[Nā hōʻike]: He kūpono ʻo Lenvatinib no ka mālama ʻana i nā maʻi o ka maʻi maʻi thyroid o ka hoʻi hou ʻana a i ʻole ke ʻano metastasis, ke ʻano holomua a me ka radioactive iodine-refractory differentiated type.