N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Hōʻike 99.0~101.0 Hale Hana

N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) AJI97 Hana Hana
ʻO ka N-Acetyl-L-Tyrosine, ke maloʻo, ʻaʻole i emi iho ma mua o 99.0 pākēneka a ʻaʻole ʻoi aku ma mua o 101.0 pākēneka o N-Acetyl-L-Tyrosine (C11H13NO4).
Wehewehe: ʻO nā keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline, ka ʻono ʻawaka ikaika
Hiki ke hoʻoheheʻe ʻia i ka wai.
Hoʻoheheʻe (H2O, g/100g): 17.5 (20 ℃), 72.4 (40 ℃), 158 (60 ℃)
ʻIke: E hoʻohālikelike i ka spectrum absorption infrared o ka hāpana me ke ʻano maʻamau ma ke ʻano pāpaʻi pāpaʻi bromide.
Ka Po'i Pono [α]20/D: La'ana malo'o, C=4, H2O
Moku'āina o ka Solution (Transmittance): 0.5g i 10ml o H2O, spectrophotometer, 430nm, 10mm ka mānoanoa pūnaewele.
Klorida (Cl): 0.7g, A-1, ref: 0.40ml o 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml o 0.005mol/L H2SO4
Ka hao (Fe): 0.5g, ref: 1.5ml o Iron Std.(0.01mg/ml)
Nā Metala Kaumaha (Pb): 2.0g, (3), ref: 2.0ml o Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), ref: 2.0ml o As2O3 Std.
Nalo ma ka maloʻo: ma 105 ℃ no 3 mau hola
Ke koena ma ka ʻāʻā (Sulfated): AJI Test 13
Ho'āʻo: Lapana maloʻo, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
ʻO Tyrosine: ʻO ka chromatography wai.Kūlana hana: ʻIke: UV absorption photometer (214nm);Kona: ODS, 4.6mm x 150mm;Ka wela o ke kolamu: ka wela lumi.Kahe kahe: 1ml / min;Māhele kaʻahele: 0.04mol/L solution o ka monopotassium phosphate (pH 4.35): Methanol (193:3)
pH: 1.25g i 50ml o H2O
Manaʻo ʻia ka palena o ka waiho ʻana a me ke kūlana: ʻO nā pahu paʻa paʻa i mālama ʻia ma ka lumi wela (2 mau makahiki).

N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) USP35 Hana Hana
HOAKAKA
Loaʻa i ka N-Acetyltyrosine ka NLT 98.5% a me ka NMT 101.0% o C11H13NO4, e like me N-Acetyl-L-Tyrosine, i helu ʻia ma ke kumu maloʻo.
IKE
A. KA PALAPALA INFRARED <197K>
B. OPTICAL ROTATION, Poali kiko'ī <781S>
Haʻina hoʻohālike: 10 mg/mL
Nā mea e ʻae ai: NLT +46.0° a me NMT +49.0°, hoʻoholo ʻia ma 20°
C. ʻO ka waiwai RF o ke kumu nui o ka hāpana laʻana i ka hoʻāʻo ʻana no nā Organic Impurities e pili ana i ko ka solution maʻamau 1.
HANA
HANA
Laʻana hoʻonā: E hoʻoheheʻe ma kahi o 180 mg o N-Acetyltyrosine, i kaupaona ʻia, i 50 mL o ka wai kalapona ʻole.
Pūnaehana Titrimetric
(E nānā i ka Titrimetry <541>)
Ke ʻano: Hoʻohālikelike pololei
Titrant: 0.1 N sodium hydroxide VS
ʻImi hope: Potentiometric
Kaulike: ʻO kēlā me kēia mL o 0.1 N sodium hydroxide VS ua like ia me 22.32 mg o C11H13NO4.
NA mea haumia
Nā mea haumia ʻole
KA HOʻOPIʻI KOE <281>: NMT 0.1%
KLORIDA A ME SULFATE, Klorida <221> NMT 200 ppm.ʻAʻole ʻoi aku ka nui o ka chloride ma mua o ka 0.40 mL o ka 0.01 N hydrochloric acid.
KLORIDA A ME SULFATE, Sulfate <221> NMT 200 ppm.ʻAʻole hōʻike ʻia kahi ʻāpana 1.2-g i ka sulfate ma mua o 0.25 mL o 0.020 N sulfuric acid.
HAAWINA <241>: NMT 20ppm
NA METAL HEAVY, Hana I <231>: NMT 10ppm
Nā mea haumia kino
HANA
Adsorbent: 0.25-mm papa o ka huila silica gel chromatographic
Haʻina waiwai maʻamau 1: 8 mg/mL o USP N-Acetyl-L-tyrosine RS i loko o ka hui ʻana o ka wai, ka ʻakika acetic glacial, a me ka waiʻona (3:3:94)
Haʻina maʻamau 1: E hoʻoheheʻe i ka solution stock maʻamau 1 me ka waiʻona no ka loaʻa ʻana o ka hopena i ʻike ʻia ma kahi o 0.4 mg/mL.
ʻO ka hoʻonā maʻamau 2: 0.8 mg/mL o USP L-Tyrosine RS i hoʻoheheʻe ʻia i loko o ka hui ʻana o ka glacial acetic acid a me ka wai (1:1), a hoʻoheheʻe ʻia me ka waiʻona.
Laʻana hoʻonā: E hoʻololi i ka 0.8 g o N-Acetyltyrosine i kahi pahu volumetric 10-mL, e hoʻoheheʻe i loko o 6 mL o ka hui ʻana o ka waikawa acetic glacial a me ka wai (1:1), a hoʻoheheʻe me ka waiʻona i ka nui.
Ka nui o ka noi: 5 µL
Ke hoʻomohala nei i ka ʻōnaehana solvent: He hui ʻana o ka ammonia a me 2-propanol (3:7)
Pahu mea hoʻoponopono: E hoʻoheheʻe i 0.2 g ninhydrin i 100 mL o ka hui ʻana o ka butanol a me ka 2 N acetic acid (95:5).
Kūpono ʻōnaehana
Nā koi kūpono: Hōʻike ka chromatogram o ka ʻōnaehana kūpono i nā wahi ʻelua i hoʻokaʻawale ʻia.
Nānā: E hoʻomau e like me ke kuhikuhi ʻia no Chromatography <621> Thin-Layer Chromatography.Ma hope o ka hoʻomaloʻo ʻana i ka ea, e hana hou i ke kaʻina hana.Ma hope o ka hoʻomaloʻo ʻana i ka ea i ka lua o ka manawa, kāpī ʻia me ka Spray reagent, a wela ma waena o 100° a me 105° no kahi 15 min.
Paʻa ʻae ʻia: ʻAʻole ʻoi aku ka nui a i ʻole ka ikaika o nā wahi lua o ka solution laʻana ma mua o ka wahi nui o ka solution maʻamau1, koe wale nō ka wahi e pili ana i ka tyrosine, ʻaʻole i ʻoi aku ka nui a i ʻole ka ikaika ma mua o ka wahi kumu o ka solution maʻamau 2.
Nā haumia o kēlā me kēia kanaka: NMT 0.5%
Ka palena o ka tyrosine: NMT 1.0%
NA HOAO KUAI
LOSSON DRYING <731>: Hoʻomaloʻo i kahi hāpana ma 105 ℃ no 3 mau hola: nalowale NMT 0.1% o kona kaumaha.
NA KOI HOU
PACKAGING a me ka mālama ʻana: E mālama i loko o nā pahu i pani maikaʻi ʻia, a e mālama i kahi mahana wela.
USP REFERENCE STANDARD <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS