N-Fluorobenzenesulfonimide (NFSI) CAS 133745-75-2 Maʻemaʻe >98.0% (HPLC) Mea Hoʻoheheʻe Fluorinating

N-Fluorobenzenesulfonimide (NFSI) (CAS: 133745-75-2), Versatile fluorinating reagent i hoʻohana ʻia i ka fluorination o nā aryls, enolates, carbanions, organolithiums, etc.
ʻO ka N-Fluorobenzenesulfonimide he mea hoʻohana maʻamau ka electrophilic fluorinating agent i ka synthesis organik e hoʻokomo i ka fluorine i loko o nā molekala organik kūʻokoʻa.Hoʻohana ʻia ia e fluorinate i nā substrates nucleophilic e like me nā ʻano organometallic reactive a me nā anion malonate.Hiki ke hana ʻia ka NFSi e ka hopena o benzenesulfonimide me ka fluorine.
ʻO N-Fluorobenzenesulfonimide he mea hou, paʻa a maʻalahi hoʻi ka fluorination reagent, hiki ke hoʻokomo i ka fluo rine atoms i loko o ke kūlana carbonyl ortho o nā molekala organik, a hiki ke hana i ka hopena monofluorination ma nā meaʻalaʻala waiwai electron, enol sila ne, ene Chemicalbook alcohol lithium paʻakai, etc. ʻO nā wahi wela o ka noiʻi ʻana i kēia manawa, ʻo ia ka hopena cyclization Nazarov i hoʻopaʻa ʻia e ka hao a i ʻole kobalt e hana i ke apo lima lālā, a me ka asymmetric catalysis o ka enantioselective α-fluorination.
N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates a me nā carbanions i nā hua kiʻekiʻe.Hoʻohana ʻia ia no ka fluorination diastereoselective o Li enolates o chiral carboximides, no ka fluorination kuhikuhi ʻana o nā mea ʻala o ka ortho-lithiated a no ka loiloi o nā mea hana fluorinating NF electrophilic.Hoʻohana ʻia nā fluorinations Asymmteric ma ke alo o kahi ʻōnaehana catalyst Pd-BINAP ma ka wela lumi i loko o kahi wai ionic.He reagent ia i ho'ohana 'ia i loko o ka palladium-catalyzed enantioselective fluorination o t-butoxycarbonyl lactones a me lactams.Hoʻohana pū ʻia ia i ka difluorination electrophilic o nā dihalopyridines me ka lithium butyl a i ka hoʻololi pololei ʻana o nā alcohols i dibenzenesulfonamides me ka triphenylphosphine.