N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Hoʻohui Hoʻohui Maʻemaʻe >99.0% (HPLC)

N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent no ka hoʻomākaukau ʻana i nā esters ikaika o nā waikawa amino.Peptide solid phase synthesis linking agent.
Hoʻohana pinepine ʻia ʻo N-Hydroxysuccinimide e kōkua i ka hui ʻana o ka peptide-mediated carbodiimide ma o ka hoʻokumu ʻana i kahi ester ester ma o ka condensation o ka hui carboxyl surface a me NHS.Hiki i ka NHS-reactive ester intermediate i ka hoʻouka kaua nucleophilic e nā amine mua a me ka hopena i ka hoʻokumu ʻana i nā paʻa amide paʻa ma waena o ka ʻili biomaterial a me ka N-terminus o ka peptide.
ʻO N-Hydroxysuccinimide kahi succinimide hydroxylated i hoʻohana nui ʻia i ka hoʻoulu ʻana o nā waikawa carboxylic i NHS-esters e hoʻoikaika i ka hui ʻana me nā nucleophiles.Hoʻohana pinepine ʻia kēia ʻano hana i ka hoʻāla ʻana i nā ʻano ʻakika manuahi o nā fluorophores no ka hoʻoikaika ʻana i ka hui ʻana o kēia mau fluorophores i nā koena amine o nā protein.Ua wehewehe ʻia ka hoʻohana ʻana i ka hoʻoulu ʻana o ka ester NHS i ka synthesis o nā waikawa amino N-acyl.
Hoʻohana ʻia no ka synthesis o ka amino acid protectant, semi-synthetic kanamycin a me pharmaceutical intermediates.N-hydroxybutyldiimide a me kāna mau derivatives he mea waiwai nui no ka synthesis o peptides, antibiotics, amino acids a me nā protein. esters, a me ka inhibition o ka optically ikaika hopena o ka peptide hui 'ana i ka laulā huahelu o USES i loko o ka lāʻau lapaʻau, a me kekahi kumu kemika maka kumu.
Hoʻohana ʻia ka N-Hydroxysuccinimide no ka hoʻomaikaʻi ʻana i nā amidations ma ke ʻano carbodiimide.Hoʻohana ʻia ia e hoʻāla i kahi hui carboxyl a hana pū me ka amine e hana i ka amide.Hoʻopili ʻia ia i ka hoʻomākaukau ʻana o N-hydroxymaleimide-styrene copolymer.