Olmesartan Medoxomil CAS 144689-63-4 Maʻemaʻe >99.5% (HPLC) API Hale Hana
ʻO Ruifu Chemical Supply Olmesartan Medoxomil Intermediates Me ke Kiʻekiʻe Kiʻekiʻe:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Inoa Kimia | ʻO Olmesartan Medoxomil |
Nā huaʻōlelo like | 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester;CS-866 |
Helu CAS | 144689-63-4 |
Helu CAT | RF-PI1730 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C29H30N6O6 |
Kaumaha Molecular | 558.60 |
Lae hehee | 180 ℃ (Dek.) |
Hiki i ka wai | ʻAʻole hiki ke hoʻonā i ka wai;Hiki ke hoʻoheheʻe ʻia ma DMSO |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keokeo a aneane keokeo Cyrstalline pauda |
ʻIkepili | IR, HPLC, UV: Pono e hoʻokō i ke kūlana kuhikuhi |
Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC ma ka Anhydrous and Solvent-Free Basis) |
Nalo ma ka maloo | <0.50% |
Koena ma ka Ignition | <0.10% |
Na mea pili | |
Olmesartan RRT 0.2 | <0.50% |
Olmesartan Medoxoil Huihui Pili A. RRT 0.7 | <0.20% |
Olefinic haumia RRT 1.6 | <0.50% |
N-Alkyl haumia RRT 3.4 | <0.10% |
ʻO nā mea haumia ʻē aʻe | <0.10% |
Huina paumaele | <0.50% |
Nā Metala Kaumaha (e like me Pb) | <10ppm |
pH o ka Haʻina (2%, W/V) | 4.5 a 6.5 |
Kūlana hoʻāʻo | ʻOihana Kūlana;USP Kūlana |
Hoʻohana | API |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) he mea ikaika a koho i ka angiotensin II type 1 (AT(1)) receptor antagonist me IC50 o 66.2 μM., i hoʻohana ʻia i ka mālama ʻana i ke koko kiʻekiʻe.Hoʻohana ʻia ma ke ʻano he anti-hypertensive.Hana ʻo Olmesartan ma ke kāohi ʻana i ka hoʻopaʻa ʻana o ka angiotensin II i nā mea hoʻokipa AT1 i ka ʻiʻo vascular.Ma ka pale ʻana i ka hoʻopaʻa ʻana ma mua o ka synthesis o angiotensin II, pale ʻo Olmesartan i nā manaʻo hoʻoponopono maikaʻi ʻole i ka huna ʻana o ka renin.ʻO Olmesartan Medoxomil kahi lāʻau lapaʻau i hoʻopau ʻia i ka metabolite ikaika, olmesartan.Ua hoʻokuʻu ʻia ʻo Olmesartan Medoxomil ma US ʻo Benicar, kahi lāʻau lapaʻau waha no ka hypertension.