Palbociclib CAS 571190-30-2 Maʻemaʻe >99.5% (HPLC) API Hale Hana
ʻO Ruifu Chemical Supply Palbociclib Nā Kūwaena Pili:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-hoʻokahi CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
Inoa Kimia | Palbociclib |
Nā huaʻōlelo like | PD-0332991;Otava-Bb 1115529;ʻO Ibrance |
Helu CAS | 571190-30-2 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C24H29N7O2 |
Kaumaha Molecular | 447.54 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pada keʻokeʻo a i ʻole keʻokeʻo |
1H NMR Spectrum | Kūlike me ka hoʻolālā |
HPLC | Kūlike me ka hoʻolālā |
Na mea pili | |
Ka haumia o ke kanaka | <0.50% |
Huina paumaele | <1.00% |
Nalo ma ka maloo | <0.50% |
Koena ma ka Ignition | <0.10% |
Nā Metala Kaumaha | <10ppm |
Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API, i ka lapaau ana i ka ma'i ma'i umauma |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Palbociclib (CAS: 571190-30-2) he mea hoʻopaneʻe i ka cyclin-dependent kinase (CDK) i loaʻa i ka waha me ka hana antineoplastic.Palbociclib koho i ka cyclin-dependent kinase 4 (CDK4) a me 6 (CDK6), no laila ke keʻakeʻa nei i ka phosphorylation protein retinoblastoma (Rb) i ka hoʻomaka ʻana o ka pae G1 e alakaʻi ana i ka hopu ʻana o ka cell cycle.Hoʻopau kēia i ka hana hou ʻana o DNA a hoʻemi i ka hoʻonui ʻana o nā cell tumor.ʻO Palbociclib ka ʻelele mua o ka papa lāʻau hou o ka cyclin-dependent kinase inhibitors.Hoʻopili kēia hopena i ka hoʻonui ʻana o ke kelepona (ka ulu ʻana a me ka māhele ʻana).Hoʻohana ʻia ia ma ke ʻano he antineoplastic agent i ka maʻi maʻi umauma holomua a metastatic paha.