Pirfenidone CAS 53179-13-8 Maʻemaʻe ≥99.0% IPF
Hoʻolako me ka hoʻomaʻemaʻe kiʻekiʻe, ka hana kalepa
Inoa Kemika: Pirfenidone
CAS: 53179-13-8
| Inoa Kimia | Pirfenidone |
| Nā huaʻōlelo like | Perfenidone;5-Methyl-1-Phenylpyridine-2(1H)-hoʻokahi;PFD;S-7701;AMR-69 |
| Helu CAS | 53179-13-8 |
| Helu CAT | RF-API108 |
| Kūlana Kūʻai | Loaʻa |
| ʻĀpana Molekala | C12H11NO |
| Kaumaha Molecular | 185.22 |
| Lae hehee | 96.0 a 97.0 ℃ |
| Ka hoʻoheheʻe | Hiki ke hoʻoheheʻe ʻia ma DMSO |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a i ka ʻulaʻula melemele Crystalline pauda |
| ʻIkepili | IR |
| Maemae | ≥99.0% |
| Nalo ma ka maloo | ≤0.50% |
| Lehu Sulfate | ≤0.20% |
| Hoʻokahi haumia | ≤0.50% |
| Huina paumaele | ≤1.0% |
| Metala Kaumaha | ≤20ppm |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | API, Idiopathic Pulmonary Fibrosis (IPF) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
Aia ʻo Pirfenidone (CAS: 53179-13-8) i kahi hui o nā lāʻau i kapa ʻia he antifibrotic agents.Ua hōʻike ʻo Pirfenidone i ka hana ma nā ʻano fibrotic he nui, e like me nā mea o ke akemāmā, ka puʻupaʻa a me ke ake.Hoʻopilikia ia i ka ʻōnaehana pale o kou kino a hoʻemi i ka nui o ka fibrosis (scaring) i loko o ka māmā.ʻO Pirfenidone kekahi o nā lāʻau ʻelua i ʻae ʻia ma Kanada e mālama i ka Idiopathic Pulmonary Fibrosis (IPF).ʻO Pirfenidone he mea hoʻopaneʻe no ka hana TGF-β a me ka TGF-β i hoʻouluʻia i ka hana collagen, ho'ēmi i ka hanaʻana o TNF-α a me IL-1β, a he mau mea anti-fibrotic a me anti-inflammatory.Ua'āpono muaʻia ma Iapana no ka mālamaʻana i nā maʻi me ka idiopathic pulmonary fibrosis ma hope o nā ho'āʻo hoʻokolohua, ma lalo o ka inoa kālepa o Pirespa e Shionogi, ma 2008. Ua'āponoʻia no ka hoʻohanaʻana i ka European Union ma 2011, ma Kanada i 2012, a ma ʻAmelika Hui Pū ʻIa i ʻOkakopa 2014.
