Posaconazole Intermediate POA CAS 149809-43-8 Hale Hana Kiʻekiʻe
Hale Hana Hoʻolako Posaconazole Pili ana i waena, hana kalepa
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Inoa | Posaconazole Intermediate POA |
Nā huaʻōlelo like | (5R-cis) -Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester;(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate |
Helu CAS | 149809-43-8 |
Helu CAT | RF-PI291 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C21H21F2N3O4S |
Kaumaha Molecular | 449.47 |
ʻO ka mānoanoa | 1.40 |
Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
Brand | ʻO Ruifu Chemical |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka hina keʻokeʻo pauda |
ʻIkepili | IR E like me ke kūlana |
Lae hehee | 100.0-102.0 ℃ |
Ka Poali Pono [a]20/D | -40.0° a i -48° (C=1, CHCl3) |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Metala Kaumaha | ≤20ppm |
Na mea pili | |
Ka haumia nui | ≤0.40% |
POA-Enantiomer | ≤0.10% |
POA-Diastereomer | ≤0.20% |
He haumia ʻike ʻole ʻia ke kanaka | ≤0.20% |
Huina paumaele | ≤1.0% |
Maemae | ≥99.0% |
Hoʻāʻo | 98.0%~102.0% (mea anhydrous) |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Waena o Posaconazole (CAS 171228-49-2) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester (CAS 149809-43 -8) ka Intermediate o Posaconazole (CAS 171228-49-2).ʻO Posaconazole kahi mea antifungal triazole e pale ana i ka synthesis o ergosterol ma ke kāohi ʻana i ka enzyme lanosterol 14α-demethylase a me ka hōʻiliʻili ʻana o nā precursors methylated sterol, ʻoi aku ka ikaika o ka inhibiting 14α-demethylase ma mua o itraconazole.