Pregabalin CAS 148553-50-8 Maʻemaʻe >99.0% (HPLC) API Antiepileptic
Mea Manufacturer me High Purity a Commercial Production
Inoa Chemical: PregabalinCAS: 148553-50-8
ʻO Pregabalin kahi lāʻau antiepileptic lua o ka hanauna (AED)
Inoa Kimia | Pregabalin |
Nā huaʻōlelo like | (S)-3-(Aminomethyl)-5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Lyrica |
Helu CAS | 148553-50-8 |
Helu CAT | RF-API57 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C8H17NO2 |
Kaumaha Molecular | 159.23 |
Lae hehee | 194.0~196.0 ℃ |
Solubility i ka wai | ʻAʻole hiki ke hoʻoheheʻe ʻia i ka wai |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o ka Ethanol |
Kūlana Hoʻouna | Ma lalo o ka mahana wela |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIkepili | IR: E like me ka mea kuhikuhi |
Hoʻololi kikoʻī | +10.0°~+13.0° (C=1, Wai) |
Nalo ma ka maloo | <0.50% |
Lehu Sulphated | <0.10% |
Na mea pili | haumia A <0.15% |
ʻO nā mea haumia ʻole i hōʻike ʻia ma mua o ka Pregabalin (hōʻike A) <0.10% | |
ʻO nā mea haumia ʻole i hōʻike ʻia ma hope o Pregabalin (hōʻike B ) <0.10% | |
Huina no ka hoao A a me B <0.50% | |
Maemae Na HPLC R-Isomer | <0.15% |
Nā Metala Kaumaha (e like me Pb) | <10ppm |
Klorida (Cl) | <0.05% |
Nā mea hoʻoheheʻe koena | |
Isopropyl Alcohol | <5000ppm |
Ethyl Acetate | <5000ppm |
Tetrahydrofuran | <250ppm |
Isopropyl Etera | <500ppm |
Ethanol | <1000ppm |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC ma ke kumu maloʻo) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API no ka Laau Laau Laau Antiepileptic |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Pale mai ka māmā a me ka makū
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ʻO Pregabalin kahi lāʻau antiepileptic lua o ka hanauna (AED) i ʻike ʻia me ka inoa inoa inoa o Lyrica (Pfizer, Tadworth) ma UK a me USA, loaʻa ka γ-amino butyric acid structure ma kona ʻano mole, nona nā hopena anticonvulsant, a ʻo ia hoʻi. Ua hoʻomohala maikaʻi ʻia e ka hui Pfizer no ka mālama ʻana i ka ʻeha neuropathic peripheral, a i ʻole ka mālama ʻana i nā ʻāpana ʻāpana.ʻO Pregabalin kahi lāʻau Anticonvulsant a me antiepileptic i hoʻohana ʻia e mālama i ka epilepsy, ʻeha neuropathic, fibromyalgia, a me ka maʻi hopohopo ākea.ʻO kona hoʻohana ʻana no ka epilepsy ma ke ʻano he add-on therapy no ka hoʻopaʻa ʻana i ka ʻāpana me ka ʻole o ka generalization lua i nā pākeke.I Dekemaba 2008, ua ʻae ka US Food and Drug Administration (FDA) i ka pregabalin (inoa kālepa "Lyrica") no ka mālama ʻana i ka ʻeha neuropathic peripheral (DPN) a me ka neuralgia postherpetic (PHN) ʻo ia nā ʻeha neuropathic maʻamau.Loaʻa i ka Pregabalin kahi hōʻailona i ʻae ʻia a hoʻohana nui ʻia no ka mālama ʻana i ka maʻi hopohopo ākea.Ua ʻike ʻia kekahi mau hoʻāʻo i hoʻopaʻa ʻia, ʻelua makapō, placebocontrolled he lāʻau maikaʻi ʻo pregabalin no nā poʻe maʻi me ka maʻi hopohopo ākea a me ka pilikia pilikanaka.ʻO ka titration epilepsy-adjunctive therapy: 25 mg bd no 7 mau lā, e hoʻonui ʻia e 50 mg i kēlā me kēia 7 lā;mālama maʻamau 300 mg i kēlā me kēia lā, hoʻokaʻawale ʻia i 2 a i ʻole 3 doses (max. 600 mg i kēlā me kēia lā, i māhele ʻia i 2 a i ʻole 3 doses).ʻO ka maʻi hopohopo nui: 150 mg i kēlā me kēia lā, hoʻokaʻawale ʻia i 2 a i ʻole 3 doses, no 7 mau lā, e hoʻonui ʻia e 150 mg i kēlā me kēia 7 mau lā (max. 600 mg i kēlā me kēia lā, i māhele ʻia i 2 a i ʻole 3 doses).Inā ho'ōki i ka pregabalin, ua ʻōlelo ʻia e hoʻopaʻa i ka liʻiliʻi ma kahi o 1 pule e pale ai i ka haʻalele koke ʻana.'Ōlelo Aʻo No nā maʻi me nā kūlana e hiki ke hoʻomaka i ka encephalopathy.ʻO nā maʻi me ka puʻuwai congestive koʻikoʻi.
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