PyAOP CAS 156311-83-0 Maʻemaʻe >99.0% (HPLC) Hui Hana Hana Hoʻohui

Hoʻohana ʻia (7-Azabenzotriazol-1-yloxy) tripyrrolidinophosphonium Hexafluorophosphate (PyAOP) (CAS: 156311-83-0) ma ke ʻano he mea hoʻohui i loko o ka peptide synthesis paʻa.Ua ʻoi aku ka maikaʻi ma mua o ka HATU, no ka mea, ʻaʻole ia e ʻaoʻao i ka N-terminus o ka peptide.Ke hoʻohālikelike ʻia i nā mea hoʻopuka HOBt, PyAOP (a me HOAt ma ka laulā) ʻoi aku ka ʻoi aku o ka hoʻoikaika ma muli o ka nitrogen hou.
ʻO ka PyAOP he paʻakai phosphonium i hoʻohana ʻia ma ke ʻano he hui hoʻohui i loko o ka solid-phase peptide synthesis, me ka loaʻa ʻole o nā hopena ʻaoʻao me ka terminal amino.ʻO ka PyAOP kahi hua o HOAt.
ʻO ka PyAOP kahi paʻakai phosphonium mai HOAt i hoʻohana i kahi peptide coupling reagent.Paʻa ʻo PyAOP ma ke ʻano he paʻa a i ka hopena DMF, kūpono i ka hana paʻa a me ka solution-based peptide synthesis, kūleʻa me nā waikawa amino sterically hindered, i ka hoʻokumu ʻana i nā peptides cyclic a i ka synthesis solid-phase o nā peptides fluorescently labeled.Loaʻa ʻo PyAOP i nā hua maikaʻi loa i ka hopena maikaʻi a hoʻopaʻa i ka racemisation.ʻO PyAOP ka pyrrolidino analogue o AOP a ua hoʻolālā ʻia me ka manaʻo o ka hana ʻana i kahi huahana liʻiliʻi ʻona ma mua o HMPA, i hana ʻia me AOP.
Reagent for synthesis of: Cyclic RGC pentapeptides for functionalization through click chemistry;Fluorescent glucose bioprobes;Kelepona kahe ReactIR™
Reagent no: ʻenehana paʻa disulfide;Heteroaryl ether synthesis;ʻO ka maikaʻi o ka conformational constraint ma non-phosphorylated cyclic peptide antagonists o ka Grb2-SH2 domain.