Pyridazine CAS 289-80-5 Maʻemaʻe >99.0% (GC) Hale Hana

ʻO Pyridazine (CAS: 289-80-5), i kapa ʻia ʻo 1,2-diazine i kekahi manawa, he apo ʻeono i loaʻa i ʻelua mau ʻātoma nitrogen pili.ʻO ka Pyridazine kahi hana hoʻohanohano i ka kemika lāʻau lapaʻau a hiki ke hoʻohana ʻia ma ke ʻano he isosteric pani o nā apo phenyl a i ʻole heteroaromatic.Hiki i nā Pyridazines ke hoʻomaikaʻi i nā waiwai physiochemical o nā molekala lāʻau ma o ka hoʻonui ʻana i ko lākou hiki ke hoʻoheheʻe ʻia i ka wai, ke komo ʻana ma ke ʻano he mea hoʻopaʻa paʻa hydrogen, a loaʻa iā ia ka mana kiʻekiʻe e paʻakikī me nā pahuhopu ma muli o ko lākou manawa dipole.Hāʻawi ʻo Pyridazine i ka bioavailability, ʻoi aku hoʻi i ka CNS, a hiki ke hōʻemi i ka ʻona.ʻO ka Pyridazine kahi ʻāpana o nā molekole lāʻau lapaʻau, a ua alakaʻi ka pyradzine pharmacophore i nā ʻano mea like ʻole o ka pharmacologically active compound.Pyridazine pili i ka heterocyclic azine pūhui i loaʻa i ka nitrogen hexaheterocyclic, ia a me pyrimidine, pyrazine he isomers o kekahi i kekahi.Hoʻohana nui ʻia ʻo Pyridazine ma ke ʻano he lāʻau lapaʻau lāʻau, e like me ka sulfa SMP no ka manawa lōʻihi he pyridazine derivative, 4-amino-cinnoline e pili ana i nā antimalarials, hydralazine lāʻau koko koko, a me nā mea ʻē aʻe.hiki ke hoʻohana ʻia e like me ka mea maka o nā pesticides, no ka hana ʻana i nā herbicides, "herbicide-sensitive", "Milstem", "bromine herbicide-sensitive".ʻO Pyridazines nā pūhui heterocyclic me kahi paʻa NN i loko o kā lākou apo.ʻO ka mole pyridazine he π-deficient heteroaromatic pūhui like me pyridine.Ma muli o ka loaʻa ʻana o ka π-deficient nitrogen aromatic heterocycles ʻoi aku ka maʻalahi o kēia mau pūhui i ka wai ke hoʻohālikelike ʻia me nā hydrocarbons ʻē aʻe.Aia i loko o ka ʻōnaehana apo aromatic kumu o pyridazine ʻelua mau ʻātoma nitrogen pili.Loaʻa ke apo Pyridazine i loko o nā herbicide he nui e like me credazine, pyridatol a me nā lāʻau lapaʻau he nui e like me cefozopran, olaparib, talazoparib, a me cadralazine.