Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Maʻemaʻe ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Hoʻolako ʻia ʻo Vonoprazan Fumarate a me Intermediate pili
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Inoa Kimia | Pyridine-3-Sulfonyl Chloride |
| Nā huaʻōlelo like | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
| Helu CAS | 16133-25-8 |
| Helu CAT | RF-PI540 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C5H4ClNO2S |
| Kaumaha Molecular | 177.61 |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Waiwai ʻole a i ʻole Melemele Pale |
| Maʻemaʻe / Kaʻina Hanana | ≥98.5% (GC) |
| Lae paila | 110.0~112.0℃/2mm Hg |
| Hoʻokahi haumia | ≤0.50% |
| Huina paumaele | ≤1.5% |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Ka waena o Vonoprazan Fumarate (CAS: 1260141-27-2) |
Pūʻolo: ʻO ka'ōmole, 25kg / Barrel, aiʻole e like me ka makemake o ka mea kūʻai.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) he mea waena o Vonoprazan Fumarate (CAS: 1260141-27-2).ʻO Vonoprazan Fumarate, i ʻike ʻia a hoʻomohala ʻia e Takeda a me Otsuka, ua ʻae ʻia e ka PMDA o Iapana i Dekemaba 2014, a ua hōʻike ʻia no ka mālama ʻana i ka maʻi maʻi ʻōpū, duodenal ulcer a me reflux esophagitis.Loaʻa i ka Vonoprazan fumarate kahi hana hou o ka hana i kapa ʻia ʻo potassium-competitive acid blockers, e hoʻokūkū hoʻokūkū i ka hoʻopaʻa ʻana o nā ion potassium iā H+, K+-ATPase (ʻike pū ʻia ʻo ka pauma proton) i ka hana hope loa o ka huna ʻana o ka ʻōpū o ka ʻōpū i loko o nā pūnaʻi parietal ʻōpū.ʻAʻole ʻae ʻo Vonoprazan i ka hana Na +, K + -ATPase a hiki i ka 500 mau manawa kiʻekiʻe ma mua o kā lākou mau waiwai IC50 e kūʻē i ka hana gastric H +, K + -ATPase.Eia kekahi, ʻaʻole i hoʻopilikia ʻia ka lāʻau lapaʻau e ka ʻōpū huna huna, ʻaʻole like me nā PPI.
