(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst CAS 112022-83-0 Maʻemaʻe Optical ≥98.0%

Mea Hana Hana;ʻO ke kūlana kiʻekiʻe a me ka uku hoʻokūkū

CBS Catalysts
(S)-(-)-2-Methyl-CBS-oxazaborolidine;(S)-Me-CBS Catalyst (ca. 1mol / L i Toluene);CAS: 112022-81-8
(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst (ca. 1mol / L i Toluene);CAS: 112022-83-0

CBS Catalyst
ʻO ka CBS catalyst a i ʻole Corey–Bakshi–Shibata catalyst he asymmetric catalyst i loaʻa mai ka proline.Loaʻa iā ia nā hoʻohana he nui i nā hopena kūlohelohe e like me ka CBS reduction, Diels-Alder reactions a me (3+2) cycloadditions.ʻO Proline, kahi hui chiral kūlohelohe, hiki ke loaʻa a maʻalahi.Hoʻololi ʻo ia i kāna stereocenter i ka catalyst a hiki iā ia ke hoʻokele i kahi pane kūlohelohe koho i kekahi o nā enantiomers ʻelua.ʻO kēia koho ma muli o ke koʻikoʻi steric i ke kūlana hoʻololi e ulu ana no hoʻokahi enantiomer akā ʻaʻole no kekahi.

CBS Catalysts no ka Hoemi Asymmetric a me Asymmetric Synthesis
Ua hoʻohana ʻia ka CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst i ka hoʻohaʻahaʻa asymmetric o nā ketones prochiral.ʻO nā noi ʻē aʻe e pili ana i ka synthesis enantioselective o α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols, a me propargyl alcohols.

(R)-(+)-2-Methyl-CBS-oxazaborolidine (ca. 1mol / L i Toluene) CAS: 112022-83-0 hiki ke hoʻohana ʻia ma ke ʻano he catalyst i ka hoʻemi ʻana o ka borane asymmetric o perfluoroalkyl ketones.ʻO nā noi ʻē aʻe e pili ana i ka synthesis enantioselective o α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, a me propargyl alcohols.Hoʻohana ʻia ia i kahi hoʻemi desymmetrizing e alakaʻi ana i (S) -4-hydroxycyclohexenone.He mea pono ia i ka hana ʻana i nā kumu stereospecific e like me α-hydroxy acids, α-amino acids, symmetrical ferrocenyl diols a me propargyl alcohols.

(R)-(+)-2-Methyl-CBS-oxazaborolidine (ca. 1mol/L i Toluene) CAS: 112022-83-0 he mea hoʻoheheʻe organoboron i hoʻohana ʻia i ka synthesis organik.ʻO kēia catalyst, i hoʻomohala ʻia e Itsuno a me Elias James Corey, i hana ʻia e ka hoʻomehana (R)-(+)-2-(diphenylhydroxymethyl) pyrrolidine me ka trimethylboroxine a i ʻole methylboronic acid.He mea hana maikaʻi loa ia no ka synthesis o nā waiʻona i ka ratio enantiomeric kiʻekiʻe.ʻO ka maʻamau, hoʻohana ʻia ka 2-10 mol% o kēia catalyst me ka borane-tetrahydrofuran (THF), borane-dimethylsulfide, borane-N,N-diethylaniline, a i ʻole diborane ma ke kumu borane.Ua hoʻohana ʻia ka hoʻohaʻahaʻa Enantioselective me ka chiral oxazaborolidine catalysts i ka synthesis o nā lāʻau lapaʻau e like me ezetimibe a me aprepitant.