(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Maʻemaʻe ≥99.0% Maʻemaʻe Chiral ≥99.0%
Inoa Kimia | (R)-(-)-3-Quinuclidinol |
Nā huaʻōlelo like | (R)-3-Quinuklinol |
Helu CAS | 25333-42-0 |
Helu CAT | RF-CC117 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C7H13NO |
Kaumaha Molecular | 127.18 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pada keʻokeʻo a i ʻole keʻokeʻo |
ʻIke RT (na GC) | Kūlike me ka Reference Standard |
Lae hehee | 212.0~224.0 ℃ |
Kahuli kiko'ī [α]D20 | -40.0°~ -48.0° |
Māmā (KF) | ≤0.50% |
Koena ma ka Ignition | ≤0.50% |
Maemae | ≥99.0% |
Huina paumaele | ≤1.00% |
Maʻemaʻe Chiral | ≥99.0% |
Enantiomer | ≤1.00% |
Hoʻāʻo | 98.0%~101.0% (ma ke kumu Anhydrous) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Huina Kiral;Nā Kūwaena Lapaʻau |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Pale mai ka māmā a me ka makū
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) me ke ʻano kiʻekiʻe, hoʻohana nui ʻia i ka synthesis organik, synthesis o nā intermediates pharmaceutical a me Hoʻohui ʻia ʻo Active Pharmaceutical Ingredient (API).(R)-(-)-3-Quinuclidinol hiki ke hoʻohana ʻia ma ke ʻano he waena i ka synthesis o API (CAS: 242478-38-2).(CAS: 242478-38-2) he lāʻau antimuscarinic i hoʻohana ʻia no ka mālama ʻana i ka ʻōpū o ka ʻōpū e hōʻike ana i nā hōʻailona o ka pinepine, wikiwiki, a i ʻole ka hoʻomau.(CAS: 242478-38-2) he M3 muscarinic receptor antagonist i hoʻomohala ʻia a hoʻokuʻu ʻia no ka mālama ʻana i ka ʻōpū overactive (pollakiuria) ma ʻEulopa.Ua hoʻopili ʻia nā mea loaʻa M3 i nā ʻokiʻoki ʻana o ka ʻiʻo maʻemaʻe o ka ʻōpū, a ua manaʻo ʻia hoʻi nā mea loaʻa M2 e pāʻani i kahi kuleana ma muli o ko lākou mana i ka ʻiʻo detrusor.ʻO ka synthesis o solifenacin e pili ana i ka hoʻomākaukau ʻana i ka racemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline ma o ka cyclization o N-(2-Phenylethyl) benzamide, a me ka hopena hope me ka ethyl chloroformate a me ka transesterification me (R) -3-Quinuclidinol .Hāʻawi ʻo Chiral chromatography i ka hoʻokaʻawale ʻana o ka diastereomer i makemake ʻia.ʻO kahi'ē aʻe, hiki ke hoʻopiliʻia ka 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline i ka hoʻonāʻana o ka optical me (+) -Tartaric Acid ma mua o ka mālamaʻana me ka ethyl chloroformate a me ka transesterification ma hope.