(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0~102.0% (HPLC) Hale Hana
ʻO Ruifu Chemical Supply Lansoprazole Intermediates
Lansoprazole CAS 103577-45-3
Lansoprazole Chloride Compound CAS 127337-60-4
(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6
Inoa Kimia | (R)-Lansoprazole |
Nā huaʻōlelo like | R-(+)-Lansoprazole;Dexlansoprazole;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;T 168390;TAK 390;Lansoprazole haumia 14;Dexlansoprazole pili i nā mea haumia 2;(R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-Benzimidazole; |
Helu CAS | 138530-94-6 |
Helu CAT | RF-PI1916 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C16H14F3N3O2S |
Kaumaha Molecular | 369.36 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka Dimethylformamide, ʻaneʻane hiki ʻole ke hoʻoheheʻe ʻia i ka wai |
Akaka a me ke kala o ka hoʻonā | Ku i ka Koi |
ʻIkepili IR | Pono e kūlike ka spectrum absorption infrared me ka mea kuhikuhi |
ʻIke HPLC | Pono ka manawa paʻa o ka piko nui e kūlike me ka mea o ka kuhikuhi |
Hoʻololi kikoʻī | +142.0°~+149.0° |
Lae hehee | ~140.0 ℃ |
Waiwai (KF) | <1.00% |
Koena ma ka Ignition | <0.10% |
Nā mea haumia pili | (HPLC) |
Nā ʻōkene Nitrogen | <0.10% |
Sulfone | <0.40% |
Sulfide | <0.20% |
ʻO nā mea haumia ʻē aʻe | <0.10% |
Huina paumaele | <0.60% |
Maʻemaʻe Optical (HPLC) | >99.5% |
Hoʻāʻo | 98.0~102.0% (HPLC, %w/w, ma ke kumu anhydrous, solvent-free) |
Nā Metala Kaumaha | <10ppm |
Nā mea hoʻoheheʻe koena | |
Toluene | <890ppm |
n-Heptana | <5000ppm |
Endotoxin maʻi bacteria | <2.5EU/mg |
Kūlana hoʻāʻo | USP Standard;Pākē Pharmacopoeia |
Hoʻohana | API;ʻO kahi mea hoʻomākeʻe i ka Pump Proton ma ka waha |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
(R)-Lansoprazole (CAS: 138530-94-6) ʻo ia ka R enantiomer o Lansoprazole, Lansoprazole (AG 1749) he mea hoʻoheheʻe pāpaʻi proton e pale ana i ka ʻōpū mai ka hana ʻana i ka waikawa.ʻO Dexlansoprazole no Lansoprazole dextroisomer, he ʻano lāʻau lapaʻau anti-peptic ulcer no ka hoʻololi ʻana i nā derivatives benzimidazole, i loko o ka molecular structure i loko o ka element fluorine, ʻelua proton pump inhibitors omeprazole ma hope.Loaʻa i ka Dexlansoprazole ka hopena o ka pale ʻana i ka huna ʻana o ka waikawa gastric, ʻoi aku ka maikaʻi o ka hopena ma mua o nā lāʻau ʻē aʻe (Omeprazole, Pantoprazole, Rebela, Tetrazolium) hiki ke pale nui i ka hiki ʻana o ka maʻi maʻi.ʻOi aku ka maikaʻi ma mua o ka famotidine a i ʻole Omeprazole no ka hōʻino ʻana i ka mucosa gastric i hoʻoiho ʻia i ka waiʻona a me ka ʻeha duodenal i kumu nui ʻia e ka hypersecretion waikawa.Eia kekahi, ua like ka hopena anti Helicobacter pylori i ka huahana e like me ka hoʻomākaukau ʻana i ka bismuth, a hoʻohana ʻia no ka reflux esophagitis a me ka maʻi Zhuo AI.Ua loaʻa i ka Takeda Pharmaceuticals ka ʻae ʻia o dexlansoprazole, he ʻano hoʻokuʻu ʻelua o ka (R) -isomer o ka lansoprazole proton pump inhibitor (PPI) i mua i ka mākeke, mai ka FDA i Ianuali 2009. ʻO Dexlansoprazole kahi capsule hoʻokuʻu lohi no ka lāʻau lapaʻau waha. ʻO ka puʻuwai e pili ana me ka maʻi hōʻailona non-erosive gastroesophageal reflux (GERD), ka ho'ōla ʻana o ka esophagitis erosive (EE) a me ka mālama ʻana i ka EE i hoʻōla ʻia.