Ramelteon Intermediate CAS 196597-78-1 Maʻemaʻe >98.5% (HPLC)
Ke alakaʻi nei i ka mea hana a me ka mea hoʻolako, nā mea waena o Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
Inoa Kimia | 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-kahi |
Nā huaʻōlelo like | 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-hoʻokahi;Ramelteon Intermediate 1;Ramelteon I |
haumia | Ramelteon haumia A |
Helu CAS | 196597-78-1 |
Helu CAT | RF2883 |
Kūlana Kūʻai | I loko o ka waihona, hana hiki ke 20 tona no ka mahina |
ʻĀpana Molekala | C11H10O2 |
Kaumaha Molecular | 174.20 |
Lae hehee | 133.0 a 137.0 ℃ |
Lae paila | 334.2±42.0 ℃ |
ʻO ka mānoanoa | 1.288±0.06 g/cm3 |
Papa Hazard | Hoʻonanea |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ʻole Melemele Paʻa Paʻa |
Maʻemaʻe / Kaʻina Hanana | >98.5% (HPLC) |
Lae hehee | 133.0 a 137.0 ℃ |
Wai (na Karl Fischer) | <0.50% |
Koena ma ka Ignition | <0.10% |
Huina paumaele | <1.50% |
1 H NMR Spectrum | Kūlike me ka hoʻolālā |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o Ramelteon (CAS: 196597-26-9) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
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Hoʻohana ʻia ʻo 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one (CAS: 196597-78-1) ma ke ʻano he waena o Ramelteon (CAS: 196597-26-9) , ka nucleus makuahine o ka synthesizing Ramelteon.ʻO Ramelteon ka mea mua i loko o kahi papa hou o nā mea hiamoe e hoʻopaʻa paʻa i nā mea loaʻa MT1 a me MT2 i ka suprachiasmatic nucleus (SCN), ma kahi o ka hoʻopaʻa ʻana i nā mea loaʻa GABA.ʻAʻole hōʻike ʻo Ramelteon i kahi paʻa maikaʻi i nā mea loaʻa GABAA, i pili pū me nā hopena anxiolytic, myorelaxant, a me nā hopena amnesic.Hiki ke hoʻohana ʻia ʻo Ramelteon no ka insomnia, ʻoi aku ka lōʻihi o ka hoʻomaka ʻana o ka hiamoe.ʻAʻole i hōʻike ʻia ʻo Ramelteon e hana i ka hilinaʻi a ʻaʻole i hōʻike i ka hiki ke hoʻomāinoino, a ʻo ka haʻalele ʻana a me ka rebound insomnia i maʻamau me GABA modulators ʻaʻole i loaʻa i ka ramelteon.Hoʻohana kekahi mau kauka i ka ramelteon no ka mālama ʻana i ka Delayed Sleep Phase Syndrome.Hoʻomaʻamaʻa ʻana i ka insomnia (pilikia i ka hiamoe ʻana).Hiki ke hoʻohana ʻia no nā kūlana ʻē aʻe e like me ka hoʻoholo ʻana e kāu kauka.ʻO Ramelteon kahi agonist melatonin.Hana ia ma ka hana ʻana i ka melatonin receptors i loko o ka lolo, e kōkua iā ʻoe e hiamoe.