Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory Maʻemaʻe Kiʻekiʻe
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | ʻO Rapamycin |
Nā huaʻōlelo like | Sirolimus;RAPA;AY-22989 |
Helu CAS | 53123-88-9 |
Helu CAT | RF-API59 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C51H79NO13 |
Kaumaha Molecular | 914.19 |
Lae hehee | 183.0~185.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ʻole ke keʻokeʻo Crystalline pauda |
ʻIkepili A | ʻO ka IR spectrum o ka potassium bromide hoʻomākaukau ʻana o ka laʻana e hōʻike ana i ka maxima ma nā hawewe like like me ka hoʻomākaukau like o ka maʻamau kuhikuhi hale. |
ʻIkepili B | ʻO ka spectrum UV o 95% ka hoʻomākaukau ʻana i ka ethanol o ka laʻana e hōʻike i ka maxima ma 267nm, 277nm, 288nm e like me ka hoʻomākaukau like ʻana o ka maʻamau kuhikuhi hale. |
ʻIkepili C | ʻO ka manawa paʻa o nā piko no nā trans-a me cis-stereoisomers i loko o ka chromatogram o ka hoʻomākaukau ʻana e pili ana i ka chromatogram o ka hoʻomākaukau maʻamau, e like me ka loaʻa ʻana ma ka hoʻāʻo. |
ʻO ka hoʻololi ʻana | -147.0°~ -157.0° |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Nā Metala Kaumaha | ≤20ppm |
Ka haumia o ke kanaka | ≤1.5% |
Huina paumaele | ≤2.0% (koe ka Cis-Stereoisomer o Sirolimus) |
Cis-Stereoisomer o Sirolimus | ≤5.0% |
Nā mea hoʻoheheʻe koena | |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
ʻO Diethyl Etera | ≤5000ppm |
Hoʻāʻo | ≥98.5% (Ka helu trans- a me cis-stereoisomer o sirolimus ma ke kumu dired) |
Kūlana hoʻāʻo | Pākē Pharmacopoeia (CP);Kūlana ʻoihana |
Hoʻohana | Mea Hana Lapaʻau Hoʻoikaika (API) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Rapamycin (Sirolimus; AY 22989) he mea hana autophagy, he ʻano hou o ka macrolide immunosuppressive agent me nā hopena curative maikaʻi, haʻahaʻa haʻahaʻa, a ʻaʻohe nephrotoxicity.Hiki ke hoʻohana ʻia no ka mālama ʻana i ka pale ʻana o nā ʻano hoʻololi (ʻoi loa i nā transplants kidney) e hoʻopau i nā hōʻole immunological ma hope o ka hoʻololi ʻana i ke kino.