Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
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N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
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Inoa Kimia | N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester |
Nā huaʻōlelo like | Remdesivir Intermediate;ʻO ke kaulahao ʻaoʻao Remdesivir;Remdesivir p-NitroPhenoxy L-Alanine haumia;Remdesivir Impurity 4;Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate |
Helu CAS | 1354823-36-1 |
Helu CAT | RF-PI297 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C21H27N2O7P |
Kaumaha Molecular | 450.42 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keokeo a aneane keokeo pauda |
ʻIkepili | IR, HPLC |
Nalo ma ka maloo | ≤1.0% |
Hoʻokahi haumia | ≤0.50% |
Nā Metala Kaumaha | ≤20ppm |
Maemae | ≥98.0% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o Remdesivir (CAS 1809249-37-3);COVID-19 |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, ʻike ʻia hoʻi ʻo Remdesivir Impurity 4) he phosphoramidate sidechain i hoʻohana maʻamau no ka hoʻomākaukau ʻana o Remdesivir (CAS. 1809249-37-3, GS-5734), he lāʻau noiʻi antiviral hou no ka mālama ʻana i ka maʻi maʻi Ebola a me nā maʻi maʻi maʻi Marburg a ma hope mai ua ʻike ʻia e hōʻike i ka hana antiviral e kūʻē i nā coronaviruses (eg SARS-Cov-2/ Covid-19).I ka puka ʻana o ka maʻi Coronavirus hou 2019 (COVID-19), ʻo Remdesivir (CAS 1809249-37-3) kekahi o nā huahana noiʻi e pili ana i ka COVID-19.ʻO Remdesivir, i kūʻai ʻia ma lalo o ka inoa inoa ʻo Veklury, kahi lāʻau lapaʻau antiviral ākea ākea i hoʻomohala ʻia e ka hui biopharmaceutical Gilead Sciences.Hāʻawi ʻia ia ma o ka injection i loko o kahi vein.I ka wā maʻi maʻi COVID-19, ua ʻae ʻia a ʻae ʻia ʻo Remdesivir no ka hoʻohana ʻana i ka pilikia e mālama i ka COVID-19 ma kahi o 50 mau ʻāina.ʻO nā alakaʻi i hoʻonui ʻia mai ka World Health Organization i Nowemapa 2020 me kahi ʻōlelo aʻoaʻo kūʻē i ka hoʻohana ʻana o Remdesivir no ka mālama ʻana i ka COVID-19.