Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
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Inoa Kimia | 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate |
Nā huaʻōlelo like | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir haumia 21 |
Helu CAS | 1911578-98-7 |
Helu CAT | RF-PI303 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C21H27N2O7P |
Kaumaha Molecular | 495.38 |
ʻO ka mānoanoa | 1.2g/cm3 |
Lae hehee | 92.0~96.0 ℃(māmā) |
Lae paila | 356.7 ℃ ma 760 mmHg |
Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
Infrared Spectrum | Kūlike i ka hoʻolālā |
Maemae | ≥99.0% |
Nalo ma ka maloo | ≤0.50% |
Hoʻokahi haumia | ≤0.50% |
Huina paumaele | ≤1.0% |
Nā Metala Kaumaha | ≤20ppm |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Ka waena o Remdesivir (CAS 1809249-37-3) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) kahi mea koʻikoʻi koʻikoʻi waena i ka hoʻomākaukau ʻana i nā analogs pili Remdesivir.ʻO Remdesivir kahi prodrug monophosphoramidate o kahi analog adenosine, he mea noiʻi antiviral ākea ākea me ka hana in vitro e kūʻē i ka SARS coronavirus, MERS coronavirus a, hou aku, Covid-19.Ua hoʻomohala nui ʻia ʻo Remdesivir ma ke ʻano he lapaʻau no nā maʻi filovirus e like me ka maʻi maʻi Ebola a i ʻole ka maʻi ʻo Marburg.Ma hope mai, ua ʻike ʻia ʻo Remdesivir e hōʻike i ka hana antiviral e kūʻē i nā maʻi RNA i hoʻopaʻa ʻia e like me ka respiratory syncytial virus, Nipah virus, Hendra virus, Junin virus, Lassa fever virus a me nā coronaviruses (me nā maʻi MERS a me SARS).I kēia mau lā ke aʻo ʻia nei he lāʻau lapaʻau hoʻohiki no ka mālama ʻana i ka COVID-19 (ʻano maʻi ʻano SARS hou).ʻO Remdesivir, i hoʻomohala ʻia e Gileada Sciences, he adenosine prodrug e hoʻololi i kāna ʻano hana GS-441524 e hoʻopilikia i ka hana o ka RNA-dependent RNA polymerase a pale i ka proofreading e viral exoribonuclease (ExoN), e hoʻemi ana i ka hana RNA viral.