ʻO Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5%~102.0% API Factory Maʻemaʻe Kiʻekiʻe
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
ʻO Rosuvastatin Calcium
CAS: 147098-20-2
Hana Kalepa
Inoa Kimia | ʻO Rosuvastatin Calcium |
Nā huaʻōlelo like | ZD 4522 Kaluma;(E)-6-[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate;(6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
Helu CAS | 147098-20-2 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C44H54CaF2N6O12S2 |
Kaumaha Molecular | 1001.14 |
Lae hehee | 122 ℃ |
Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
Hoʻololi kikoʻī | +17.0° ~ +21.0° |
ʻIkepili | H. Kupono i ke koi B. UV: λmax=243nm C. IR: E like me ka mea kuhikuhi D. X-Ray: E like me ka mea kuhikuhi |
Klorida | ≤0.10% |
Sulphate | ≤0.10% |
Enantiomer | ≤0.15% |
Maʻiʻo Calcium | 3.5%~4.5% |
Na mea pili | |
Diastereomer | ≤0.15% |
5-Oxo-Rosucastatin | ≤0.15% |
Hoʻohaʻahaʻa kiʻi 1 | ≤0.15% |
Hoʻohaʻahaʻa kiʻi 2 | ≤0.15% |
ʻO Rosuvastatin Lactone | ≤0.15% |
ʻO Rosuvastatin Methyl Ester | ≤0.15% |
ʻO Rosuvastatin Isoamyl Ester | ≤0.15% |
ʻO ka haumia ʻike ʻole ʻia | ≤0.10% |
Huina paumaele | ≤0.75% |
Māmā (KF) | ≤3.0% |
Metala Kaumaha | ≤20ppm |
Isoamil Bromide | ≤37.5ppm |
Nā mea hoʻoheheʻe koena | |
Ethyl Etera | ≤300ppm |
Acetonitrile | ≤410ppm |
ʻO ka waiʻona Isoamyl | ≤5000ppm |
DMF | ≤880ppm |
Hoʻāʻo | 98.5%~102.0% (caculated ma ke kumu anhydrous) |
Kūlana hoʻāʻo | ʻOihana Kūlana;Kūlana BP/USP/EP |
Hoʻohana | API |
Pūʻolo: ʻO ka'ōmole, Barrel, Cardboard drum, 25kg / Barrel, aiʻole e like me ka makemake o ka mea kūʻai
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Pale mai ka malamalama, ka makū
ʻO Rosuvastatin Calcium (CAS: 147098-20-2) kahi lāʻau anti-hyperlipidemia nona ka mea hoʻopale o HMG-CoA reductase i hoʻomohala maikaʻi ʻia e ka hui Pelekane ʻo AstraZeneca.He kūpono ia no ka mālama ʻana i nā ʻano like ʻole o ka lipid, me ka hypercholesterolemia, nā ʻano like ʻole o ka lipid qualitative a me ka hypertriglyceridemia maʻalahi.Ua helu ʻia ʻo Rosuvastatin Calcium (CAS: 147098-20-2) ʻo ia ka lāʻau statins ikaika a piha loa i komo i ka mākeke no ka hoʻohaʻahaʻa lipid a me ka hoʻoponopono.Ke hoʻohālikelike ʻia me ka atorvastatin i ʻike ʻia me ka maikaʻi loa o ka honua, ʻoi aku ka maikaʻi o ka hoʻohaʻahaʻa ʻana i ke kiʻekiʻe o ka LDL cholesterol a me ka hoʻonui ʻana i ke kiʻekiʻe o ka lipoprotein kiʻekiʻe.Eia kekahi, ʻoi aku ka maikaʻi o ka hoʻomanawanui, nā hopena haʻahaʻa haʻahaʻa a me nā hiʻohiʻona pharmacokinetic kūikawā me ka hapalua o ke ola e pili ana i 20h.