(S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Maʻemaʻe ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Hāʻawi Kalepa ʻo Palonosetron Hydrochloride a me nā mea e pili ana i waena:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Inoa Kimia | (S)-3-Aminoquinuclidine Dihydrochloride |
| Nā huaʻōlelo like | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Helu CAS | 119904-90-4 |
| Helu CAT | RF-CC112 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C7H16Cl2N2 |
| Kaumaha Molecular | 199.12 |
| ʻO ka mānoanoa | 1.24g/cm3 |
| Lae hehee | 260 ℃ |
| Lae paila | 470.4 ℃ ma 760mmHg |
| Solubility i ka wai | Hiki ke hoʻoheheʻe |
| Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a i ka ʻulaʻula melemele Crystalline pauda |
| IR | Absorption Spectra Kūlike me ka Reference |
| Pane Kloride | Hoʻoholo maikaʻi |
| Maʻemaʻe (HPLC) | ≥98.0% |
| Nalo ma ka maloo | ≤0.50% |
| Kahuli kiko'ī [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Nā Metala Kaumaha | ≤20ppm |
| Waihona | 5-8 ℃ Paʻa ea |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | Palonosetron Hydrochloride (CAS: 135729-62-3) Kūwaena |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Alanui Synthetic
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) me ke kūlana kiʻekiʻe.He lāʻau lapaʻau maʻamau i ka synthesis o Palonosetron Hydrochloride (CAS: 135729-62-3).
ʻO Palonosetron Hydrochloride (CAS: 135729-62-3) he lāʻau lapaʻau e pale ai i ka nausea a me ka luaʻi ʻana, he ʻano hou i koho nui ʻia, kiʻekiʻe-affinity 5-HT3 receptor antagonist hiki ke pale i ka luaʻi reflex center peripheral neurons presynaptic 5-HT.Hoʻopili pololei ka hauʻoli o ka mea hoʻokipa i ka ʻōnaehana kikowaena waena ma 5-HT.Hoʻoulu ʻia ka hauʻoli o ka mea loaʻa i ka vagal afferent ma hope o ka wahi, ke kāohi ʻana i nā hopena nerve vagus i loko o ka ʻōpū, e pale ana i nā hōʻailona i 5-HT.Hiki i ka Receptor trigger zone ke hoemi i ka nui o ka nausea a me ka luai.ʻO ke kikowaena kikowaena no ka mālama ʻana i ka chemotherapy emetogenic koʻikoʻi i hoʻoulu ʻia i ka nausea a me ka luaʻi ʻana.Ma muli o kona hopena curative kiʻekiʻe, hopena ʻaoʻao liʻiliʻi, lōʻihi ka hapalua o ke ola (e pili ana i 40 h), liʻiliʻi liʻiliʻi, a pēlā aku, ua huki nui ia.Me ka 1,2,3,4-tetrahydro-1-naphthoic acid e like me ka mea hoʻomaka, ka māhele, amination, hōʻemi, cyclization, paʻakai o palonosetron hydrochloride granisetron.Ua hōʻike ʻia nā haʻawina lāʻau lapaʻau e hiki ke hoʻohana palekana ʻia ka palonosetron me nā corticosteroids, analgesics, antiemetics, antispasmodics a me nā lāʻau anticholinergic e like me ka mea hoʻomaka, ka māhele, amination, hōʻemi, cyclization, paʻakai o ka palonosetron hydrochloride granisetron.
