Telmisartan CAS 144701-48-4 Maʻemaʻe >99.5% (HPLC) API Hale Hana
ʻO Ruifu Chemical Supply Telmisartan Intermediates Me ka Maʻemaʻe Kiʻekiʻe
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)ʻakika benzoic CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Inoa Kimia | Telmisartan |
Nā huaʻōlelo like | 4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Carboxylic Acid |
Helu CAS | 144701-48-4 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C33H30N4O2 |
Kaumaha Molecular | 514.63 |
Lae hehee | 261.0~263.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ʻole ke keʻokeʻo Crystalline pauda |
ʻala | ʻano ʻano |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka Methylene Chloride, Souble liʻiliʻi i ka Methanol, ʻAʻole hiki ke hoʻoheheʻe ʻia i ka wai, Hoʻoheheʻe ʻia i loko o 1M Solution Hydroxide. |
IR Identification | Pono e pili i ka RS Infrared Absorption |
ʻIkepili HPLC | Pono ka Manawa Paʻa o ka Puʻupuʻu Nui e like me RS |
Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC) |
Nalo ma ka maloo | <1.00% |
Koena ma ka Ignition | <0.10% |
Na mea pili | |
ʻO ka hui ʻo Telmisartan pili A | <0.10% |
ʻO Telmisartan Amide | <0.10% |
ʻO ka hui ʻo Telmisartan pili B | <0.10% |
ʻO Telmisartan Diacide | <0.10% |
Telmisartan Tert-Butyl Ester | <0.20% |
Telmisartan He haumia ʻike ʻole | <0.20% |
Ka haumia ʻole i hōʻike ʻia | <0.10% |
Huina paumaele | <1.00% |
Nā mea hoʻoheheʻe koena | |
Methanol | <0.30% |
Ethanol | <0.50% |
Methylene Dichloride | <0.06% |
n-Hexane | <0.029% |
Acetic Acid Ethyl Ester | <0.50% |
Toluene | <0.089% |
Acetic Acid | <0.50% |
Nā Metala Kaumaha | <10ppm |
Arsenic (As) | <1.00ppm |
Ke kēpau (Pb) | <1.00ppm |
Cadmium (Cd) | <1.00ppm |
Ka nui o ka ʻāpana | D90 ʻAʻole ʻoi aku ma mua o 15μm |
ʻOi aku ka nui (g/cc) | 0.11~0.20 |
Paʻi ʻia (g/cc) | 0.22~0.30 |
Pesticide koena | ʻinoʻino |
Huina Papa | <1000cfu/g |
Huna & Mold | <100cfu/g |
E. Coli | ʻinoʻino |
Salmonella | ʻinoʻino |
Kūlana hoʻāʻo | ʻOihana Kūlana;USP 41 Kūlana |
Hoʻohana | API |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Telmisartan (CAS: 144701-48-4) kahi derivative benzimidazole a me kahi antagonist receptor non-peptide angiotensin II me ka waiwai antihypertensive.Hoʻopili ʻo Telmisartan i ka angiotensin II i hoʻopaʻa ʻia i ka AT1 subtype receptor, aia i loko o ka ʻiʻo palupalu vascular a me ka gland adrenal.ʻO ka antagonism ka hopena i ka vasodilation a keʻakeʻa i ka hana aldosterone i ka angiotensin II-mediated aldosterone, kahi e alakaʻi ai i ka emi ʻana o ka sodium a me ka wai a me ka hoʻonui ʻana i ka excretion potassium e alakaʻi ana i kahi hōʻemi o ke koko.ʻO Telmisartan kahi ʻano lāʻau hou o ke koko, hoʻohana wale ʻia a i hui pū ʻia me nā papa antihypertensives ʻē aʻe no ka mālama ʻana i ka hypertension.Ua hoʻokumu mua ʻia ʻo Telmisartan e ka hui lāʻau lapaʻau Kelemania ʻo Boehringer Ingelheim;Ua loaʻa iā ia ka patent German EP502,314 i ka makahiki 1991, ua ʻae mua ʻia e komo i ka mākeke ʻAmelika i Nowemapa 1998, a laila komo i ka German, Philippines, Australian, Belgium, British, a me nā mākeke ʻē aʻe.