Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% API Factory
Nā Mea Kūʻai Kūʻai ʻo Tenofovir e pili ana:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Inoa Kimia | ʻO Tenofovir Disoproxil Fumarate |
Nā huaʻōlelo like | Tenofovir DF;Bis(POC)-PMPA Fumarate;GS 4331 Fumarate |
Helu CAS | 202138-50-9 |
Helu CAT | RF-API106 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C23H34N5O14P |
Kaumaha Molecular | 635.52 |
Lae hehee | 113.0 a 115.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda keʻokeʻo a ʻaneʻane keʻokeʻo |
ʻIkepili A | Kūlike ʻo IR Spectrum i ka maʻamau kuhikuhi |
ʻIkepili B | ʻO ka manawa paʻa o ke kiʻekiʻe nui mai ka hāpana hāpana e like me kēlā o ka solution standrd, e like me ka loaʻa ʻana ma ka hoʻāʻo. |
Hoʻāʻo | 98.0%~102.0% (ma ke kumu anhydrous) |
Wai | ≤1.0% |
ʻAkaʻuma Fumaric | 17.5%~19.0% |
Koena ma ka Ignition | ≤0.20% |
Nā Metala Kaumaha | ≤20ppm |
Chloromethyl Isopropyl Carbonate | ≤0.15% |
Na mea pili | |
ʻO Tenofovir | ≤0.15% |
Adenine | ≤0.15% |
ʻO Tenofovir Isoproxi Monoester | ≤1.0% |
ʻO Tenofovir Disoproxil Ethyl Ester | ≤0.15% |
ʻO Tenofovir Isopropyl Isoproxil | ≤0.30% |
ʻO Tenofovir Disoproxil Carbamate | ≤0.15% |
ʻO Tenofovir Disproxil | ≤0.15% |
ʻO kēlā me kēia haumia hoʻokahi | ≤0.10% |
Huina paumaele | ≤2.0% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), he prodrug o tenofovir (Ka inoa kālepa: Viread) i hoʻomohala ʻia e Gilead Sciences, he ʻano lāʻau antiretroviral nucleotide-analogues, e hana ana ma o ka hana ʻana ma ke ʻano he reverse transcriptase inhibitors[nRTIs] , ka mea e ālai ana i ka reverse transcriptase, he enzyme koʻikoʻi i ka hana viral i ka poʻe i loaʻa i ka maʻi HIV.Pono e hoʻomaopopo ʻia ʻo ia ka nucleotide reverse transcriptase inhibitor mua i hoʻohana ʻia no ka mālama ʻana i ka maʻi HIV.Hoʻololi ʻia ʻo Tenofovir Disoproxil Fumarate i tenofovir in vivo, ʻo ia ka acyclic nucleoside phosphonate[nucleotide] analog o adenosine 5'-monophosphate.Hoʻohana pinepine ʻia ia me nā ʻano lāʻau lapaʻau ʻē aʻe.ʻAʻole hiki i nā lāʻau lapaʻau HIV ke hoʻōla i ka maʻi HIV/AIDS, akā ʻo ka lawe ʻana i ka hui pū ʻana o nā lāʻau HIV [i kapa ʻia he HIV regimen] i kēlā me kēia lā hiki ke kōkua i ka poʻe me ka maʻi HIV e ola lōʻihi a olakino.Ma muli o ka palapala FDA, hiki nō hoʻi i ka tenofovir disoproxil fumarate ke mālama i ka maʻi hepatitis B mau loa [HBV] i nā mākua a me nā keiki 12 makahiki a keu.