tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Maʻemaʻe >98.0% (HPLC) Palbociclib Intermediate Factory
ʻO Ruifu Chemical Supply Palbociclib Nā Kūwaena Pili:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-hoʻokahi CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
Inoa Kimia | tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate |
Nā huaʻōlelo like | 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate |
Helu CAS | 571189-16-7 |
Helu CAT | RF-PI1850 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C14H20N4O4 |
Kaumaha Molecular | 308.33 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | ʻEleʻele ʻulaʻula i ka pauda ʻeleʻele |
Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) |
LCMS | Kūlike me ka hoʻolālā |
Nalo ma ka maloo | <1.00% |
Huina paumaele | <2.00% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o Palbociclib (CAS: 571190-30-2) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) he mea waena o Palbociclib (CAS: 571190-30-2).ʻO Palbociclib (ʻike ʻia ʻo ka helu helu PD-0332991) he lāʻau hoʻokolohua no ka mālama ʻana i ka maʻi maʻi umauma e hoʻomohala ʻia e Pfizer.He mea hoʻopale koho ia o ka cyclin-dependent kinases CDK4 a me CDK6.Hoʻopaʻa ʻo Palbociclib i ka holomua o ka pōʻai cell mai ka pae G1 a i ka S ma ke kāohi ʻana i ka CDK4/6-dependent retinoblastoma (RB) phosphorylation.Ua hoʻohana ʻia ʻo Palbociclib no ka mālama ʻana i ka HER2 maikaʻi ʻole, estrogen receptor (ER) positive metastatic breast cancer.