Tolvaptan CAS 150683-30-0 API Maʻemaʻe >99.0% (HPLC)
Mea Hoʻolako ʻia ʻo Tolvaptan a me nā mea pili i waena:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| inoa | Tolvaptan |
| Inoa Kimia | N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Helu CAS | 150683-30-0 |
| Helu CAT | RF-API101 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C26H25ClN2O3 |
| Kaumaha Molecular | 448.94 |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
| Nā ʻano ʻike | IR, HPLC |
| Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o Benzyl Alcohol a me Methanol akā ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai a me ka Hexane. |
| Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) |
| Lae hehee | 219.0~222.0 ℃ |
| Nalo ma ka maloo | <0.50% |
| Koena ma ka Ignition | <0.10% |
| Hoʻokahi haumia | <0.50% |
| Huina paumaele | <1.00% |
| Nā Metala Kaumaha | ≤20ppm |
| Nā mea hoʻoheheʻe koena | E hālāwai me ka wehewehe |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | API;Nā Kūwaena Lapaʻau |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Tolvaptan (CAS: 150683-30-0), i kapa ʻia ʻo OPC-41061, he mea hoʻokūkū hoʻokūkū arginine vasopressin receptor 2 antagonist i hoʻohana ʻia no ka mālama ʻana i ka hyponatremia (mau kiʻekiʻe o ka sodium koko haʻahaʻa) pili me ka puʻuwai congestive, cirrhosis, a me ka maʻi o ʻO ka hormone antidiuretic kūponoʻole (SIADH).ʻO Otsuka Pharmaceutical laikini tolvaptan ma lalo o ka inoa kālepa Samsca ma hope o ka ʻae ʻana o ka FDA i ka lāʻau lapaʻau ma Mei 2009. Ua hōʻike pū ʻo Tolvaptan i ka maikaʻi e kūʻē i ka maʻi maʻi maʻi polycystic.I ka makahiki 2004, ua ʻike ʻia ka tolvaptan i lawelawe ʻia me nā diuretics kuʻuna e hoʻonui i ka excretion o ka nui o ka wai a hoʻomaikaʻi i ke kiʻekiʻe o ka sodium koko i nā poʻe maʻi me ka puʻuwai ʻole me ka hana ʻole ʻana i nā hopena ʻaoʻao e like me ka hypotension (ke koko haʻahaʻa) a i ʻole hypokalemia (hoʻemi i ke kiʻekiʻe o ke koko o ka potassium).ʻAʻole i hōʻike ʻia ka lāʻau lapaʻau i kahi hopena maikaʻi ʻole i ka hana ʻāʻī.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
