Tranexamic Acid CAS 1197-18-8 Assay 99.0~101.0% (Titration)
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o Tranexamic Acid (CAS: 1197-18-8) me ke kūlana kiʻekiʻe.Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai i ka Tranexamic Acid,Please contact: alvin@ruifuchem.com
| Inoa Kimia | ʻAka Tranexamic |
| Nā huaʻōlelo like | trans-4-(Aminomethyl) cyclohexanecarboxylic Acid;trans-Tranexamic Acid;TAMCHA;AMCHA;HAKU;AMCA;t-AMCHA;trans-Amcha |
| Kūlana Kūʻai | Ma ke Kahua, Hana Hana Kūʻai |
| Helu CAS | 1197-18-8 |
| ʻĀpana Molekala | C8H15NO2 |
| Kaumaha Molecular | 157.21 g/mol |
| Lae hehee | >300 ℃ (māmā) |
| Paʻa | Hygroscopic |
| Hiki i ka wai | Hiki ke hoʻoheheʻe ʻia i ka wai, ʻaneʻane hiki ke ʻike |
| COA & MSDS | Loaʻa |
| Laʻana manuahi | Loaʻa |
| Ke kumu | Shanghai, Kina |
| Brand | Kemika Ruifu |
| Nā mea | Nā kikoʻī | Nā hualoaʻa |
| Ka nana aku | Pauda Crystal Keʻokeʻo | Hoʻokō |
| Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o ka wai a me ka ʻakika acetic glacial, ʻaneʻane ʻaʻole hiki ke hoʻoheheʻe ʻia i ka ethanol a me ka acetone (96%) | Hoʻokō |
| IR Spectrum | Ma ka Concordance me Tranexamic Acid CRS | Hoʻokō |
| pH | 7.0~8.0 | 7.32 |
| Nalo ma ka maloo | <0.50% | 0.06% |
| Lehu Sulphate | <0.10% | 0.02% |
| Nā Metala Kaumaha (Pb) | ≤10ppm | <10ppm |
| Klorida (Cl) | ≤140ppm | <140ppm |
| Arsenic (As) | ≤2ppm | <2ppm |
| Hoʻāʻo | 99.0~101.0% (ma ka Titration) | 99.84% |
| Na mea pili | ||
| haumia A | <0.10% | 0% |
| haumia B | <0.20% | 0.0815% |
| haumia C | <0.10% | 0.0089% |
| haumia D | <0.10% | 0.0063% |
| Huina paumaele | <0.20% (koe ka A,B) | 0.015% |
| Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia | |
Pūʻolo:ʻO ka ʻōmole Fluorinated, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E hoʻopaʻa paʻa i ka pahu a mālama i loko o kahi hale kūʻai maloʻo a maloʻo (2 ~ 8 ℃) a me kahi hale kūʻai maikaʻi mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
Hoʻouna:Hāʻawi i ka honua ma ka lewa, e FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
ʻAka Tranexamic
C8H15NO2 157.2
trans-4-(Aminomethyl)cyclohexanecarboxylic acid;
Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans [1197-18-8].
HOAKAKA
Loaʻa ka Tranexamic Acid i ka NLT 99.0% a me NMT 101.0% o C8H15NO2, i helu ʻia ma ke kumu maloʻo.
IKE
• Hoʻopili ʻia ka Infrared <197K>
HANA
• Kaʻina hana
Laʻana hoʻonā: 140 mg o Tranexamic Acid i loko o 20 mL o glacial acetic acid
Pūnaehana Titrimetric
(E nānā i ka Titrimetry <541>.)
Ke ʻano: Hoʻohālikelike pololei
Titrant: 0.1 N perchloric acid VS
ʻImi hope: Potentiometric
Kānāwai
Laʻana: Laʻana hoʻonā
E hoʻokaʻawale me 0.1 N perchloric acid VS, e hoʻoholo i ka hopena me ka potentiometric.E hana i kahi titration hakahaka.
ʻO kēlā me kēia mL o 0.1 N perchloric acid ua like ia me 15.72 mg o C8H15NO2.
Nā pae hoʻoholo: 99.0% -101.0% ma ke kumu maloʻo
NA mea haumia
Nā mea haumia ʻole
• Ke koena ma ka Ignition <281>: NMT 0.1%;Hoʻohana ʻia ka laʻana 1-g
• Nā Metala Kaumaha, Hana II <231>: NMT 10 ppm
• Chloride and Sulfate, Chloride <221>: ʻAʻole hōʻike ʻia kahi hapa 0.51-g i ka chloride ma mua o ka like me 0.1 mL o 0.020 N hydrochloric acid (0.014%).
Nā mea haumia kino
• Kaʻina hana
Mahele Mobile: E hoʻoheheʻe i 11.0 g o ka sodium phosphate anhydrous monobasic i 500 mL o ka wai, a hoʻohui i 5 mL o triethylamine, a ukali ʻia e 1.4 g o ka sodium lauryl sulfate.Hoʻoponopono me ka waika phosphoric diluted (10% w/w) i kahi pH o 2.5, a hoʻoheheʻe me ka wai i 600 mL.Hoʻohui i kēia hoʻonā me 400 mL o ka methanol.
Haʻina kūpono ʻōnaehana: 0.2 mg/mL o USP Tranexamic Acid RS a me 0.002 mg/mL o USP Tranexamic Acid Related Compound C RS i ka wai
Haʻina maʻamau: 50 µg/mL o USP Tranexamic Acid RS i ka wai
Laʻana hoʻonā: 10 mg/mL o Tranexamic Acid i loko o ka wai
Pūnaehana Chromatographic
(E nana Chromatography <621>, Pūnaehana Pono.)
Ke ano: LC
ʻIke: UV 220 nm
kolamu: 4.6-mm × 25-cm;5-µm paʻi L1
Kahe kahe: 1 mL / min
Ka nui o ka hoʻopio: 20 µL
Ka manawa holo: 3 manawa o ka manawa paʻa o ka waika tranexamic
Kūpono ʻōnaehana
Laʻana: Haʻina kūpono ʻōnaehana
Nā koi kūpono
Hoʻoholo: NLT 2.0 ma waena o Tranexamic Acid a me 0.002 mg/mL o tranexamic acid pili pūhui C
Kānāwai
Nā Laʻana: Haʻina maʻamau a me ka hāʻina Laʻana
E helu i ka pākēneka o kēlā me kēia haumia ma ka ʻāpana o ka Tranexamic Acid i lawe ʻia:
Ka hopena = (rU/rS) × (CS/CU) × (0.1F)
rU = pane kiʻekiʻe no kēlā me kēia haumia mai ka hāʻina Laʻana
rS = pane kiʻekiʻe no ka waikawa tranexamic mai ka hoʻonā maʻamau
CS = ka manaʻo o ka USP Tranexamic Acid RS i loko o ka hoʻonā maʻamau (µg/mL)
CU = ka hoʻopaʻa ʻana o ka ʻakika Tranexamic i ka hāʻina Laʻana (mg/mL)
F = kumu pane pili (e nānā i ka Papa Hoʻomaʻemaʻe 1)
Nā pae ʻae ʻae
Nā haumia o kēlā me kēia kanaka: E nānā i ka Papa Hoʻomaʻemaʻe 1.
Huina haumia: NMT 0.2%
[E hoʻomaopopo-Hoʻowahāwahā i kekahi kiʻekiʻe ma lalo o 0.025%.]
Helu 1
Inoa Hoʻopaʻa Manawa Pilina Mea Manaʻo Manaʻo E ʻae ʻia, NMT (%)
Tranexamic acid related compound Aa 2.1 1 0.1
Tranexamic acid pili pūhui Bb 1.5 1.2 0.2
Tranexamic acid pili pūhui Cc 1.1 0.005 0.1
Tranexamic Acid 1.0 1.0 —
Huihui pili waika Tranexamic Dd 1.3 0.006 0.1
he trans, trans-4,4¢-(Iminodimethylene)di(cyclohexanecarboxylic)ʻakika.
b cis-4-(Aminomethyl) cyclohexanecarboxylic acid.
c (RS)-4-(Aminomethyl) cyclohex-1-enecarbocylic acid.
d 4-Aminomethyl benzoic acid.
NA HOAO KUAI
• Pohō ma ka ho'omalo'o <731>: Ho'omalo'o 1.00 g ma 105 ma lalo o ka momi no 2 h.Nalo ia NMT 0.5% o kona kaumaha.
NA KOI HOU
• Hoʻopaʻa a me ka mālama ʻana: E mālama i loko o nā pahu paʻa, a mālama i kahi mahana ʻaʻole i ʻoi aku ma mua o 30.
• Nā Kūlana Kūlana USP <11>
USP Tranexamic Acid RS Kaomi e nānā i ke kūkulu
USP Tranexamic Acid Pili Pili C RS
(RS)-4-(Aminomethyl)cyclohex-1-enecarbocylic acid.
C8H13NO2 155
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Nā hōʻailona pōʻino Xi - Hoʻonāukiuki
Nā Code Risk 36/37/38 - He mea hoʻonāukiuki i nā maka, ʻōnaehana hanu a me ka ʻili.
Ka wehewehe palekana
S26 - Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
S36 - E hoʻohana i nā lole pale kūpono.
S37/39 - E hoʻohana i nā mīkina lima kūpono a me ka pale maka/maka
WGK Kelemānia 2
RTECS GU8400000
HS Code 2922491100
PILI PILI
ʻAiʻona LD50 i nā ʻiole, nā ʻiole (mg/kg): 1500, 1200 iv (Melander)
ʻO Tranexamic Acid (CAS: 1197-18-8) he mea hoʻoheheʻe ʻia o ka amino acid lysine. ʻO Tranexamic acid (kūʻai pinepine ʻia ma ke ʻano papa e like me Lysteda a ma ke ʻano IV e like me Cyklokapron ma US a me Transamin, Transcam ma Asia, a me Espercil ma ʻAmelika Hema) ua kuhikuhi pinepine ʻia no ka nui o ke koko.ʻO ka waikawa Tranexamic kahi antifibrinolytic e hoʻokūkū i ka hoʻoulu ʻana o ka plasminogen i ka plasmin, kahi mole ke kuleana no ka hōʻino ʻana o ka fibrin.ʻO Fibrin ke kumu kumu no ka hoʻokumu ʻana i ke koko i loko o ka hemostasis. ʻO ka waika Tranexamic ma kahi o 8 mau manawa i ka hana antifibrinolytic o kahi analogue kahiko, ε-aminocaproic acid.Ua patent mua ia ma 1957 a loaʻa i kāna ʻae mua ʻana i ka US i ka makahiki 1986. Tranexamic Acid Applicaiton Hoʻohana ʻia e like me nā mea hoʻonaninani keʻokeʻo Ua hoʻohana nui ʻia ia ma ke ʻano o ka ʻokiʻoki, ka lāʻau lapaʻau kūloko, urology, obstetrics and gynecology, etc. ke kahe ʻana o ke koko i ka wā o ka ʻoki ʻana, a me nā mea ʻē aʻe. Ua manaʻo ʻia ʻo ia he lāʻau hemostatic, i hoʻohana nui ʻia no ka hemostasis ma hope o ke ʻoki nui a me ka postpartum.ʻOiaʻiʻo, ʻo ka hemostasis paha ke kumu liʻiliʻi e hoʻohui ʻia ai ka nui o nā toothpastes e manaʻolana e loaʻa kahi hopena.
Tranexamic Acid (CAS: 1197-18-8)
ʻoki puʻuwai
Hoʻohana maʻamau ʻia i ka ʻoki ʻana i ka naʻau, me ka ʻole o ka cardiopulmonary bypass.Hoʻololi ia i ka aprotinin.
ʻO ke koko koko
Hoʻohana ʻia e like me ka lāʻau lapaʻau nonhormonal mua o ke koko ʻōpū dysfunctional, a me ke koko kaumaha e pili ana me nā fibroids uterine.Ua hōʻike ʻia kahi noiʻi hou i nā poʻe maʻi i mālama ʻia me ka waika tranexamic e ulu aʻe ka thrombosis a me ka necrosis i kā lākou fibroids, a hiki ke hopena i ka ʻeha a me ke kuni.
Ka hopena keʻokeʻo
Ua hōʻike ʻia nā noiʻi maʻi lapaʻau no nā makahiki he hiki i ka waika tranexamic ke hoʻoheheʻe i kahi kiko me ka wikiwiki, e kōkua ana e hōʻike i kahi ʻili keʻokeʻo a nani.ʻO ka hopena wehe ʻana o ka waika tranexamic ma kahi o 50 mau manawa ma luna o ka Vitamin C, a he 10 mau manawa ma luna o AHA.ʻO ka palena o ka hoʻohana ʻana he 2%-3%, a ma nā mea hoʻonaninani ka nui ma kahi o 0.5%
1. Paʻa maikaʻi
Ke hoʻohālikelike ʻia me nā mea keʻokeʻo kuʻuna, tranexamic acid ka paʻa kiʻekiʻe, ka waikawa a me ke kūpaʻa alkali, a ʻaʻole maʻalahi i ka hopena o ke kaiapuni;ʻAʻohe pale lawe, ʻaʻohe pōʻino ʻōnaehana hoʻouna, ʻaʻohe hoʻoulu.
2. He maʻalahi ka'ōnaehanaʻili
He kūpono loa ia no nā kiko uila, keʻokeʻo a me ke kaulike ʻana i ka leo ʻili holoʻokoʻa.Ma kahi o ka hoʻomaʻamaʻa ʻana i nā kiko, hiki i ka waika tranexamic ke hoʻomaikaʻi i ke ʻano o ka ʻili o ka ʻili āpau a me ka dullness o ka nui o ka ʻili kūloko.
3. Hiki iā ia ke hoʻopau i nā kikoʻeleʻele, nā freckles melemele, nā kaha haki, etc
Hoʻokumu ʻia nā kiko ʻeleʻele e ka pōʻino o UV a me ka ʻelemakule ʻili a me nā kumu ʻē aʻe.Hiki i ka clotting acid ke pale i ka hana o nā tyrosinase a me nā melanocytes, e ho'ēmi i ka hanaʻana o ka melanin mai ka papa basal o ka epidermis, a me ka hopena o ka weheʻana i nā kikoʻulaʻula.
4. Palekana kiʻekiʻe
ʻO ka manaʻo kiʻekiʻe loa i nā mea hoʻonaninani he 2% ~ 3%.
5. Keʻokeʻo hopena
He kūpono ka Tranexamic Acid i nā ʻano ʻili āpau no ka wehe ʻana i ka pigmentation, ka ʻili keʻokeʻo a me ka hōʻemi ʻana i nā kiko, e like me: Pigmentation ma hope o ka ʻike ʻana o ka lā;Nā kikoʻeleʻele;ʻili paʻakikī;ʻO kaʻeha a me ka mumū;Ma hope o ka hana ʻana ma hope o ka laser, ka mālama ʻana i nā kukui pulsed.
