Valsartan CAS 137862-53-4 Hōʻike 98.0~102.0% API
Hāʻawi ka mea hana iā Valsartan a me nā mea pili e pili ana:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Inoa Kimia | ʻO Valsartan |
Nā huaʻōlelo like | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
Helu CAS | 137862-53-4 |
Helu CAT | RF-API32 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C24H29N5O3 |
Kaumaha Molecular | 435.52 |
Lae hehee | 116.0~117.0 ℃ |
Paʻa | Hygroscopic |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda keʻokeʻo a i ʻole keʻokeʻo;ʻAʻala ʻole, Hygroscopic |
ʻIkepili | Kūlike ka spectrum IR o ka hāpana me ka spectrum maʻamau kuhikuhi |
ʻIkepili | ʻO ka manawa paʻa o ka piko nui i loko o ka chromatogram o ka hoʻomākaukau assay e pili ana i ka hoʻomākaukau maʻamau, e like me ka loaʻa ʻana ma ka Assay. |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i loko o ka Methanol a me ka Ethanol, hiki ke hoʻoheheʻe ʻia i ka ethylacetate, hiki ke hoʻoheheʻe ʻia i ka Dichloromethane, hiki ke hoʻoheheʻe ʻia i ka wai. |
Māmā (KF) | ≤1.00% |
ʻAi ʻana (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Nā mea pili (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Hoʻokahi i ʻike ʻole ʻia i ka ʻino | ≤0.10% |
Huina paumaele | ≤0.30% (Koe ʻole D-Valsartan) |
Nā mea hoʻoheheʻe koena (GC) | |
Methanol | ≤3000ppm |
Ethyl Acetate | ≤5000ppm |
N,N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC i helu ʻia ma ke kumu anhydrous, solvent-free kumu) |
Kūlana hoʻāʻo | ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP) |
Hoʻohana | Mea Hana Lapaʻau Hoʻoikaika (API) |
Valsartan (CAS: 137862-53-4) Ke Kaʻina Hana Hana Hana
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o Valsartan (CAS: 137862-53-4) me ke ʻano kiʻekiʻe.ʻO Valsartan kahi nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, hiki ke loaʻa i ke koko kiʻekiʻe a me ka noiʻi naʻau.
ʻOi aku ka ikaika o nā hopena antihypertensive o Valsartan ma mua o ka enalapril a kūpono ia no ka mālama ʻana i ka hypertension, ka haʻahaʻa a me ka haʻahaʻa haʻahaʻa haʻahaʻa, a me ke kiʻekiʻe kiʻekiʻe o ka hypertension ma muli o ka pōʻino o ka renal.Hiki iā ia ke hoʻemi nui i ka proteinuria no nā poʻe maʻi kiʻekiʻe me ka maʻi maʻi a i ʻole nā hana maʻamau o ka ate, a hiki iā ia ke hoʻoikaika i ka ʻakika uric a me ka sodium urinary e pale ai i ka puʻupaʻa.He kūpono hoʻi ʻo Valsartan no ka hōʻemi ʻana i ka make cardiovascular no nā mea maʻi kiʻekiʻe (left ventricular failure or dysfunction) ma hope o ka loaʻa ʻana o ka puʻuwai puʻuwai.