Vidarabine (Ara-A) CAS 5536-17-4 Maʻemaʻe≥99.0% (HPLC) Hale Hana Mea Kiʻekiʻe
Hāʻawi ka mea hana i nā Arabinonucleosides Intermediates me ka maʻemaʻe kiʻekiʻe
Vidarabine;Ara-A;CAS: 5536-17-4
Arabinofuranosyluracil;Ara-U ;CAS: 3083-77-0
Cytarabine;Ara-C;CAS: 147-94-4
Inoa Kimia | Vidarabine |
Nā huaʻōlelo like | Ara-A;Arabinoadenosine;Adenine 9-β-D-Arabinofuranoside;Vira-A |
Helu CAS | 5536-17-4 |
Helu CAT | RF-PI220 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C10H13N5O4 |
Kaumaha Molecular | 267.25 |
Brand | ʻO Ruifu Chemical |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ʻole ke keʻokeʻo Crystalline pauda |
Ka hoʻoheheʻe | ʻAʻole kala |
Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
ʻIke UV | ≥98% (ma ke kumu maloʻo) |
Ka Poali Pono [a]D20 | -56.0°~-65.0° (C=1 i DMF) |
Adenine | ≤0.50% |
Adenosine | ≤0.50% |
Ara-U | ≤0.50% |
Lae hehee | 260.0~265.0 ℃ |
Metala Kaumaha | ≤20ppm |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Ka Mahana Waihona | E mālama i ka 0 ~ 8 ℃ |
Hoʻohana | API;Nā Kūwaena Lapaʻau |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Vidarabine (CAS: 5536-17-4), he lāʻau antiviral e kūʻē i nā maʻi maʻi herpes simplex a me varicella zoster.ʻO Vidarabine (CAS: 5536-17-4) kahi neurotransmitter e hana ma ke ʻano he agonist endogenous i makemake ʻia ma nā subtypes receptor adenosine.ʻO Vidarabine (CAS: 5536-17-4) kahi mea hoʻopale o A cyclase a me DNA Polymerase.ʻO Adenine 9-beta-D-arabinofuranoside (ara-A) he purine nucleoside i hana ʻia i hoʻohana ʻia i ka noiʻi hōʻailona kelepona.Ua hoʻohana pinepine ʻia i ka noiʻi anti-viral me nā maʻi hepadnaviridae a me nā maʻi herpes simplex.Hoʻopilikia ka nucleoside ara-A i ka synthesis DNA viral, akā aia wale nō ma kāna ʻano phosphorylated ikaika.
ʻO Vidarabine (CAS: 5536-17-4) kahi lāʻau lāʻau nucleoside i hoʻokaʻawale ʻia mai Streptomyces antibioticus.Loaʻa iā ia kekahi mau waiwai antineoplastic a he hana ākea ākea e kūʻē i nā maʻi DNA i loko o nā moʻomeheu cell a me ka hana antiviral koʻikoʻi e kūʻē i nā maʻi i hoʻokumu ʻia e nā maʻi like ʻole e like me nā maʻi herpes, ka VACCINIA VIRUS a me ka maʻi varicella zoster.Hiki i ka Vidarabine (CAS: 5536-17-4) ke pale aku i nā mutants acyclovir-resistant/TK-deficient o HSV a me VZV, no ka mea, ua phosphorylated ia i kona ʻano vidarabine-triphosphate ikaika e nā kinases cellular a ʻaʻole hilinaʻi i kona hoʻāla ʻana ma ka viral TK.