Xylitol CAS 87-99-0 Assay 98.5~101.0% Factory High Quality

Xylitol (CAS: 87-99-0) USP39-NF34
HOAKAKA
Aia ka Xylitol i ka NLT 98.5% a me NMT 101.0% o C5H12O5, i helu ʻia ma ke kumu anhydrous.
IKE
• A. KA PALAPALA INFRARED <197K>
Laʻana: ʻAʻole i hoʻomaloʻo ʻia
B. ʻO ka manawa paʻa o ka Xylitol peak o ka Sample solution e pili ana i kēlā o ka solution Standard, i loaʻa ma ka Assay.
HANA
• HANA
Māhele kelepona: Acetonitrile a me ka wai (20:80)
ʻO ka hopena kūpono o ka ʻōnaehana: 2.5mg/mL o USP Galactitol RS a me 25mg/mL o USP Xylitol RS ma ka pae Mobile
Haʻina maʻamau: 25mg/mL o USP Xylitol RS ma ka pae Mobile
Laʻana hoʻonā: 25mg/mL o Xylitol i ka pae Mobile
Pūnaehana Chromatographic
(E nana Chromatography <621>, Pūnaehana Pono.)
Ke ano: LC
ʻIke: UV 192 nm
kolamu: 8.0-mm x 30-cm;7-μm paʻi L34
Ka wela o ke kolamu: 80°
Kahe kahe: 0.5mL / min
Ka nui o ka injection: 25μL
Kūpono ʻōnaehana
Laʻana: Haʻina kūpono kūpono a me ka hopena maʻamau
[NĀ MEA-ʻO nā manawa paʻa pili no ka xylitol a me ka galactitol ma kahi o 1.0 a me 1.10, kēlā me kēia.]
Nā koi kūpono
Hoʻoholo: NLT 2.0 ma waena o galactitol a me xylitol, ʻO ka hopena kūpono o ka ʻōnaehana
Hoʻokaʻawale maʻamau pili: NMT 2.0%, Haʻina maʻamau
Kānāwai
Nā Laʻana: Haʻina maʻamau a me ka hāʻina Laʻana
E helu i ka pākēneka o xylitol (C5H12O5) ma ka ʻāpana o ka hāpana i lawe ʻia:
Ka hopena = (rU/rS) x (CS/CU) x 100
rU= pane kiʻekiʻe o xylitol mai ka Haʻina Haʻawina
rs= pane kiʻekiʻe o ka xylitol mai ka hopena maʻamau
CS= ka manaʻo o ka USP Xylitol RS i ka hopena maʻamau (mg/mL)
CU= ka hoʻopaʻa ʻana o ka hāpana laʻana (mg/mL)
Nā pae hoʻohālikelike: 98.5% -101.0% ma ke kumu anhydrous
NA mea haumia
• KĀMĀ KOE <281>: NMT 0.5%
Holoi i kēia mau mea:
• METAL HEAVY <231>: NMT 10ppm, me ka hoʻohana ʻana i 2g o Xylitol i hoʻoheheʻe ʻia i loko o 25mL o ka wai •(Official 1-Jan-2018)
• E HOemi i ke ko
Laʻana: 500mg
Nānā: E hoʻoheheʻe i ka Laʻana ma 2.0mL o ka wai i loko o kahi pahu conical 10-mL.I loko o ka ipu like, paipu 2mL o kahi solution dextrose 0.5mg/mL.I loko o kēlā me kēia ipu e hoʻohui i 1mL o ka alkaline cupric tartrate TS, wela a hoʻolapalapa, a maʻalili.
Paʻa e ʻae ʻia: ʻO NMT kēlā me kēia turbidity i loko o ka pahu xylitol i loko o ka pahu dextrose, kahi e puka mai ai kahi ʻeke ʻulaʻula-ʻulaʻula (0.2% hoʻohaʻahaʻa kō, e like me dextrose).
• KA LAHI O NA POLYOL EA
Māhele kelepona: Acetonitrile a me ka wai (20:80)
ʻO ka hopena kūpono o ka ʻōnaehana: 0.5mg/mL kēlā me kēia USP L-Arabinitol RS, USP Galactitol RS, USP Mannitol RS, a me USP Sorbitol RS, a me 100mg/mL o USP Xylitol RS ma ka pae Mobile.
ʻO ka hopena maʻamau: 0.5mg/mL kēlā me kēia USP L-Arabinitol RS, USP Galactitol RS, USP Mannitol RS, a me USP Sorbitol RS ma ka pae Mobile.
Laʻana hoʻonā: 100mg/mL o Xylitol i ka pae Mobile
Pūnaehana Chromatographic
(E nana Chromatography <621>, Pūnaehana Pono.)
Ke ano: LC
ʻIke: UV 192 nm
kolamu: 8.0-mm x 30-cm;7-μm paʻi L34
Ka wela o ke kolamu: 80°
Kahe kahe: 0.5mL / min
Ka nui o ka injection: 25μL
Kūpono ʻōnaehana
Nā Laʻana: Haʻina kūpono ʻōnaehana a me ka hopena maʻamau
[NOTE-ʻO nā manawa paʻa pili no L-arabinitol, mannitol, xylitol, galactitol, a me sorbitol ma kahi o 0.76, 0.81, 1.0, 1.12, a me 1.22.]
Nā koi kūpono
Hoʻoholo: NLT 1.5 ma waena o nā piko polyol āpau e pili ana, ʻO ka hoʻonā kūpono ʻōnaehana
Hoʻokaʻawale maʻamau pili: NMT 5.0% no ke kiʻekiʻe galactitol, Haʻina maʻamau
Kānāwai
Nā Laʻana: Haʻina maʻamau a me ka hāʻina Laʻana
E helu i ka pākēneka o kēlā me kēia polyol (L-arabinitol, galactitol, mannitol, a i ʻole sorbitol) ma ka ʻāpana o ka laʻana i lawe ʻia:
Ka hopena = (rU/rS) x (CS/CU) x 100
rU= pane kiʻekiʻe o ka polyol pākahi mai ka Haʻina Haʻawina
rS= pane kiʻekiʻe o ka polyol pākahi mai ka hoʻonā maʻamau
CS = ka hoʻopaʻa ʻana o ka polyol pākahi i ka hopena maʻamau (mg/mL)
CU= ka hoʻopaʻa ʻana o ka hāpana laʻana (mg/mL)
Paʻa ʻae: ʻO ka huina o nā polyols he NMT 2.0%, helu ʻia ma ke kumu anhydrous.
NA HOAO KUAI
• KA HOʻOHAʻI WAI, Ke ʻano I <921>: NMT 0.5%
NA KOI HOU
• PACKAGINGAND STORAGE: E mālama i loko o nā pahu paʻa maikaʻi.
• USP REFERENCE STANDARD <11>
USP L-Arabinitol RS
USP Galacticol RS
USP Mannitol RS
USP Sorbitol RS
USP Xylitol RS

Xylitol (CAS: 87-99-0) JP16
ʻO Xylitol, ke maloʻo, ʻaʻole i emi ma lalo o 98.0% o C5H12O5.
Hōʻike ʻia ʻo Xylitol ma ke ʻano he kristal keʻokeʻo a i ʻole ka pauka.He ʻala ʻole a he ʻono kona.
Hiki ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka ethanol (95).
He hygroscopic.
ʻIke (1) I ka 1 mL o ka hopena o Xylitol (1 i ka 2) e hoʻohui i 2 mL o ka hao (II) sulfate TS a me 1 mL o ka hopena o ka sodium hydroxide (1 i ka 5): hana ʻia ke kala uliuli-ʻōmaʻomaʻo me ka ʻole o ka turbidity. .
(2) E hoʻoholo i ke ʻano o ka infrared absorption spectrum o Xylitol, i hoʻomaloʻo mua ʻia, e like me ke kuhikuhi ʻana ma ke ʻano pāpaʻi pāpaʻa bromide ma lalo o Infrared Spectrophotometry <2.25>, a hoʻohālikelike i ke kikoʻī me ka Spectrum Reference: hōʻike nā kikoʻī ʻelua i ka ikaika like o ka absorption ma nā helu nalu like. .
pH <2.54> E hoʻoheheʻe i ka 5.0 g o Xylitol i 10 mL o ka wai i hoʻolapalapa hou ʻia a hoʻoluʻu: ʻo ka pH o kēia hopena ma waena o 5.0 a me 7.0.
Ka helu hehee <2.60> 93.0-95.0 ℃
Maʻemaʻe (1) Maʻemaʻe a me ke kala o ka hoʻonā-E hoʻoheheʻe i 5 g o Xylitol i 10 mL o ka wai: maopopo ka hopena a ʻaʻohe kala.
(2) Chloride <1.03>-E hana i ka ho'āʻo me 2.0 g o Xylitol.E hoʻomākaukau i ka hoʻonā mana me 0.30 mL o 0.01 mol/L hydrochloric acid VS (ʻaʻole ʻoi aku ma mua o 0.005%).
(3) Sulfate <1.14>-E hana i ka ho'āʻo me 4.0 g o Xylitol.E hoʻomākaukau i ka hopena hoʻomalu me 0.50 mL o 0.005 mol/L sulfuric acid VS (ʻaʻole iʻoi aku ma mua o 0.006%).
(4) Nā metala kaumaha <1.07> -E hoʻomau me 4.0 g o Xylitol e like me ke ʻano 1, a hana i ka hoʻāʻo.E hoʻomākaukau i ka hoʻonā hoʻomalu me 2.0 mL o ka mea hoʻonā alakaʻi maʻamau (ʻaʻole ʻoi aku ma mua o 5 ppm).
(5) Nickel-Dissolve 0.5 g o Xylitol i 5 mL o ka wai, hoʻohui i 3 kulu o dimethylglyoxime TS a me 3 kulu o ka ammonia TS, a ʻae e kū no 5 mau minuke: ʻaʻohe kala ʻulaʻula i hana ʻia.
(6) Arsenic <1.11>-E hoʻomākaukau i ka hopena hoʻāʻo me 1.5 g o Xylitol e like me ke ʻano 1, a hana i ka hoʻāʻo (ʻaʻole ʻoi aku ma mua o 1.3 ppm).
(7) Sugars-E hoʻoheheʻe i 5.0 g o Xylitol i 15 mL o ka wai, e hoʻohui i 4.0 mL o ka waika hydrochloric dilute, a me ka wela i loko o ka ʻauʻau wai no 3 mau hola ma lalo o kahi condenser reflux.Ma hope o ka hoʻoluʻu ʻana, hoʻokaʻawale me ka sodium hydroxide TS (hōʻailona: 2 kulu o ka methyl alani TS).A laila e hoʻohui i ka wai e hana ai i 50 mL, e hoʻololi i 10 mL o kēia wai i loko o kahi ipu, e hoʻohui i 10 ML o ka wai a me 40 mL Fehling's TS, e hoʻolapalapa mālie no 3 mau minuke, a ʻae e kū e hoʻoheheʻe i ke keleawe (I) oxide.Wehe i ka wai supernatant ma o kahi kānana aniani (G4), a holoi i ka eha me ka wai mahana a hiki i ka holoi ʻana hope ʻaʻole i hōʻike i ka alkalinity.E kānana i kēia mau holoi ma o ke kānana aniani i ʻōlelo ʻia ma luna.E hoʻoheheʻe i ka eha i loko o ka pahu i 20 mL o ka hao (III) sulfate TS, kānana i ka hopena ma o ke kānana aniani i ʻōlelo ʻia ma luna, holoi me ka wai, hoʻohui i ka holoi ʻana me ka filtrate, wela ma 80 ℃, a titrate <2.50> me 0.02 mol/L potassium permanganate VS: ʻaʻole i ʻoi aku ma mua o 1.0mL o 0.02 mol/L pāhana permanganate VS i pau.
ʻAʻole iʻoi aku ma mua o 1.0% (1 g, i loko o ka vacuum, phosphorus (V) oxide, 24 mau hola).
ʻAʻole i ʻoi aku ma mua o 0.1% (1 g).
Assay E kaupaona pololei ma kahi o 0.2 g o Xylitol, i hoʻomaloʻo mua ʻia, e hoʻoheheʻe ʻia i loko o ka wai a hiki i ka 100 mL.Pipet 10 mL o kēia hoʻonā i loko o ka ipu iodine, e hoʻohui i 50 mL o ka potassium periodate TS pololei, a wela i ka ʻauʻau wai no 15 mau minuke.Ma hope o ka hoʻoluʻu ʻana, hoʻohui i 2.5 g o ka potassium iodide, pani, lulu maikaʻi, e ʻae e kū no 5 mau minuke i kahi wahi pouli, a hoʻokaʻawale <2.50> me 0.1 mol/L sodium thiosulfate VS (hōʻailona: 3 mL o ka starch TS).Hana i kahi hoʻoholo hakahaka.
ʻO kēlā me kēia mL o 0.1 mol/L sodium thiosulfate VS＝1.902 mg o C5H12O5
ʻO nā pahu a me ka mālama ʻana i nā pahu pahu-paʻa paʻa.