High Quality LCZ696 Intermediate - 5-Azacytosine CAS 931-86-2 Purity ≥98.0% (HPLC) High Purity – Ruifu

   Manufacturer with High Purity and Stable Quality
   Commercial Supply Pyrimidine Base Intermediates

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

   Manufacturer with High Purity and Stable Quality

   Commercial Supply Pyrimidine Base Intermediates

5-Azacytosine CAS: 931-86-2 can inhibits the growth of Escherichia coli and used as the most effective cytosine mimics for the design of novel antiviral and anti-tumor drug candidates. 5-Azacytidine is a chemical analog of cytidine and acts as a hypomethylating agent. 5-Azacytidine is a DNA methyltransferase inhibitor that induces the demethylation and reactivation of silenced genes. It is an epigenetic modifier and chemical analogue of cytidine, a DNA and RNA nucleotide. 5-Azacytidine is reported to inhibit the proliferation of several cancer cell lines by reducing hypermethylation and is useful for stem cell research as it can enhance the differentiation of embryonic stem cells into cardiomyocytes and reset the epigenetic memory of mouse IPS cells. A recent study reported that 5-Azacytidine in conjunction with PDGF-AB can induce the conversion of somatic cells into tissue-regenerative multipotent stem cells. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity.