1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3 Purity > 98.0% (HPLC) Brexpiprazole Intermediate Factory
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Tshuaj npe | 1-(1-Benzothiophen-4-yl)piperazine Hydrochloride |
Synonyms | Brexpiprazole Intermediate 2;1-Benzo[b]thien-4-yl-Piperazine Hydrochloride;1-Benzo[b]thien-4-ylpiperazine Monohydrochloride |
CAS Nr | 913614-18-3 |
CAT Number | Qauv TSIS MUAJ: RF-PI1034 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 100MT / Xyoo |
Molecular Formula | C12H15ClN2S |
Molecular Luj | 254.7789 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Kev txheeb xyuas | Lub sijhawm khaws cia ntawm tus qauv ua raws li tus qauv siv |
Purity / Analysis Method | > 99.0% (HPLC) |
Poob rau ziab | <0.50% |
Dej (KF) | <0.50% |
Residue ntawm Ignition | <0.20% |
Yam khoom muaj feem | (HPLC) |
Txhua tus neeg impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Brexpiprazole (CAS: 913611-97-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride (CAS: 913614-18-3) yog ib qho nruab nrab ntawm Brexpiprazole (CAS: 913611-97-9).Brexpiprazole yog ib hom atypical antipsychotic.Nws yog dopamine D2 receptor ib nrab agonist.Raws li ib qho tshiab serotonin-dopamine kev ua haujlwm modulator, nws tuaj yeem siv rau kev kho mob schizophrenia, thiab rau kev kho mob rau kev nyuaj siab.Nws kuj tseem tuaj yeem muab kev ua tau zoo thiab kev zam dhau los ntawm kev tsim kho cov kev kho mob ua rau muaj kev nyuaj siab ntxhov siab (MDD).Cov tshuaj muaj ib tug tshwj xeeb pharmacological profile, ua raws li ib feem agonist ntawm serotonin 5-HT1A thiab dopamine D2 receptors thiab raws li ib tug tag nrho antagonist ntawm 5-HT2A thiab noradrenaline α1B / 2C receptors, nrog zoo sib xws subnanomolar binding affinity.Cov tshuaj, uas yog tsim los ntawm Otsuka thiab Lundbeck, tau pom zoo nyob rau hauv 2015 los ntawm FDA rau kev kho mob ntawm schizophrenia thiab raws li ib tug adjunctive kev kho mob rau kev nyuaj siab.