1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2 Aripiprazole Intermediate Purity > 99.0% (HPLC)
Chaw tsim tshuaj paus Supply Intermediates ntawm Aripiprazole Nrog High Purity
Aripiprazole API CAS 129722-12-9
Tom ntej: 1-(2,3-Dichlorophenyl) Piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
Tshuaj npe | 1-(2,3-Dichlorophenyl)piperazine Hydrochloride |
Synonyms | 2,3-DCPP HCl;1-(2,3-Dichlorophenyl)piperazine HCl;Aripiprazole EP Impurity B;Aripiprazole Related Compound C |
CAS Nr | 119532-26-2 |
CAT Number | Qauv TSIS MUAJ: RF-PI2268 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 30 MT / Lub Hlis |
Molecular Formula | C10H12Cl2N2 · HCl |
Molecular Luj | 267.58 Nws |
Melting Point | 245.0 ~ 247.0 ℃ |
Cia & rhiab heev | Hygroscopic.ambient kub |
Solubility hauv dej | Soluble hauv dej |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White hmoov |
Purity / Analysis Method | > 99.0% (HPLC) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.10% |
Ib leeg Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Heavy Metals (raws li Pb) | ≤ 20ppm |
Infrared Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Aripiprazole (CAS: 129722-12-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Hygroscopic.Khaws kom deb ntawm dej / noo noo thiab oxidizing tus neeg sawv cev.Khaws lub thawv kaw kom nruj thiab muab tso rau hauv qhov chaw txias, qhuav thiab zoo ventilated.Khaws nyob rau hauv inert gas
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1-(2,3-Dichlorophenyl)piperazine Hydrochloride (CAS: 119532-26-2) yog ib qho tseem ceeb nruab nrab ntawm Aripiprazole (CAS: 129722-12-9).Aripiprazole yog ib yam tshiab ntawm cov lipid soluble quinoline derivatives, nws cov tshuaj pharmacological yam ntxwv yog tias nws tsis yog tsuas yog postsynaptic dopamine D 2 receptor antagonist, tab sis kuj yog presynaptic dopamine D 2 receptor agonist, nws kuj tuaj yeem ua rau D 1, D 3, D 4 receptors;nws muaj ob qhov cuam tshuam ntawm kev ua kom ib nrab lossis receptor antagonistic ntawm 5-HT 1A receptor;Nws muaj qhov ua tsis ncaj ncees kiag li ntawm 5-HT 2A receptor.Qhov no feature yog txawv los ntawm thawj tiam, thiab atypical antipsychotics uas yog mus rau lub thib ob tiam antipsychotic tshuaj, thiab yog li ntawd nws yog hu ua dopamine system stabilizer los yog thib peb tiam antipsychotic.Txij li thaum nws yog muag hauv khw, nws yog tsuas yog siv rau hauv kev kho mob schizophrenia, kev kho mob ntawm kev puas siab puas ntsws thiab lwm yam kev puas siab puas ntsws.Raws li cov ntaub ntawv, aripiprazole muaj qhov cuam tshuam loj rau tus mob schizophrenia zoo thiab tsis zoo cov tsos mob thiab kev ntxhov siab, kev nyuaj siab, kev txawj ntse, thaum muaj kev nyab xeeb dua.Nws kuj tau tshaj tawm tias cov tshuaj kuj tuaj yeem kho lwm yam kev puas siab puas ntsws, xws li kev xav tsis zoo ntawm manic episodes, senile dementia cuam tshuam nrog kev puas siab puas ntsws, kev ntxhov siab, kev nyuaj siab, menyuam yaus kev coj cwj pwm, kev nyuaj siab.Tam sim no, Bristol-Myers Squibb thiab Otsuka Pharmaceutical Company tau tshaj tawm tias European Union tau pom zoo Abilify (aripiprazole) hauv kev kho mob schizophrenia daim ntawv thov.
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