1-Adamantanamine CAS 768-94-5 Purity > 98.0% (GC)
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Tshuaj npe | 1-Adamantanamine |
Synonyms | Amantadine;1-Aminoadamantane;1-Adamantylamine;Adamantan-1-Amine;Tricyclo[3.3.1.13,7]decane-1-amine |
CAS Nr | 768-94-5 : kuv |
CAT Number | Qauv TSIS MUAJ: RF-PI2286 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 20 MT / Lub Hlis |
Molecular Formula | C10H17 N |
Molecular Luj | 151.25 Nws |
Qhov ntom | 1.066 g / cm3 |
rhiab heev | Huab cua Sensitive |
Solubility (Soluble hauv) | Methanol;Soluble hauv Organic Solvents.Insoluble hauv dej |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau lub teeb daj hmoov los yog Crystal |
Purity / Analysis Method | > 98.0% (GC) |
Purity / Analysis Method | 97.5 ~ 102.5% (Titration los ntawm HClO4) |
Melting Point | 207.0 ~ 209.0 ℃ |
Moisture (KF) | <0.50% |
Residue ntawm Ignition | <0.50% |
Tag nrho cov impurities | <2.00% |
Solubility hauv 1 N HCl | Tsis muaj xim rau daj daj, Ntshiab rau me ntsis Hazy 5% Pass |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Pharmaceutical Intermediates |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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1-Adamantanamine, tseem hu ua Amantadine los yog 1-Aminoadamantane los yog 1-Adamantylamine (CAS: 768-94-5) ua raws li cov catalyst hauv enantioselective strecker cov tshuaj tiv thaiv ntawm phosphinoyl imines.Nws kuj tseem siv tau rau kev sib txuas ntawm adamantane derivatives, piv txwv li Amantadine Hydrochloride.1-Adamantanamine yog ib tug tswv cuab ntawm chav kawm ntawm adamantanes uas yog siv nyob rau hauv kev lag luam kws tshuaj raws li antiviral thiab ib tug antiparkinsonian tshuaj.Kev kho mob Parkinsonism nrog kev sib xyaw ntawm Levodopa, tshuaj anticholinergic, thiab amantadine muab cov txiaj ntsig zoo dua li kev siv cov tshuaj no ib leeg.Nws yog ib qho tsis muaj zog antagonist ntawm NMDA glutamate receptor, uas tuaj yeem nce qhov tso tawm ntawm dopamine thiab thaiv qhov rov ua dua ntawm dopamine.Cov tshuaj kuj tseem tuaj yeem txhawb kev tso tawm ntawm norepinephrine los ntawm cov hlab ntsha hauv lub hlwb.Nws tuaj yeem kho dyskinesia ntawm tus kab mob Parkinson thiab txhim kho dyskinesia tom qab kev kho mob dopaminergic ntev.
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