1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity
Chaw tsim tshuaj paus Supply Irinotecan thiab Related Intermediates:
Tom ntej: Irinotecan Hydrochloride CAS 100286-90-6
Irinotecan Dawb Base CAS: 97682-44-5
Tom ntej: Irinotecan Hydrochloride Trihydrate CAS 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS TSIS TAU: 86639-52-3
Tom ntej: 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Tshuaj npe | 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
CAS Nr | 143254-82-4 |
CAT Number | Qauv TSIS MUAJ: RF-PI243 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C11H20Cl2N2O |
Molecular Luj | 267.2 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog lub teeb daj hmoov |
Assay | ≥98.0% (HPLC) |
Poob rau ziab | ≤ 1.0% |
Hnyav Hlau | ≤ 20ppm |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Irinotecan Hydrochloride (CAS: 100286-90-6) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
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Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) nrog cov khoom zoo.Nws yog ib qho nruab nrab feem ntau hauv kev sib txuas ntawm Irinotecan Hydrochloride (CAS: 100286-90-6), DNA Topoisomerase I Inhibitor.
lrinotecan hydrochloride, semi-synthetic, dej soluble derivative ntawm lub hwj chim anticancer tus neeg sawv cev camptothecin, twb launched nyob rau hauv Nyiv rau kev kho mob ntawm lub ntsws, zes qe menyuam, thiab ncauj tsev menyuam.lrinotecan exerts nws antitumor kev ua los ntawm inhibition ntawm topoisomerase I, ib tug cellular enzyme uas koom nyob rau hauv kev tswj cov topographic qauv ntawm DNA thaum lub sij hawm tus txheej txheem ntawm kev txhais lus, transcription, thiab mitosis.lrinotecan tau dhau los ua de-esterification hauv vivo kom tau txais txiaj ntsig metabolite, SN-38, uas yog 1000-fold muaj zog dua li niam txiv.Txawm hais tias tsis muaj tshuaj lom ntau dua li camptothecin, ntau tus neeg mob hauv kev sim tshuaj tau pom muaj kev phiv ntawm leukopenia, raws plab, xeev siab, thiab alopecia.