1-Methylindazole-3-Carboxylic Acid CAS 50890-83-0 Purity > 99.0% (HPLC) Granisetron Hydrocholride Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-Methylindazole-3-Carboxylic Acid (CAS: 50890-83-0) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com
Tshuaj npe | 1-Methylindazole-3-Carboxylic Acid |
Synonyms | 1-Methyl-1H-Indazole-3-Carboxylic Acid |
impurity | Granisetron Related Compound D;Granisetron EP impurity D |
CAS Nr | 50890-83-0 |
CAT Number | TIAB SA 2673 |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 25 Tons ib Hlis |
Molecular Formula | C9H8N2O2 |
Molecular Luj | 176.18 Nws |
Melting Point | 213.0 ~ 218.0 ℃ |
Boiling Point | 383.7 ± 15.0 ℃ |
Qhov ntom | 1.35 ± 0.1g / cm3 |
Solubility hauv dej | Insoluble hauv dej.Soluble hauv DMSO thiab Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
Purity / Analysis Method | > 99.0% (HPLC cheeb tsam) |
Purity / Analysis Method | 99.0 ~ 102.5% (Titration los ntawm NaOH) |
Melting Point | 213.0 ~ 218.0 ℃ |
Poob rau ziab | <0.50% |
Sulfated tshauv | <0.10% |
Yam khoom muaj feem | |
Indazole Acid | <0.50% |
2-Methylindazole Acid | <0.50% |
Lwm Ib Leeg Impurity | <0.50% |
Total Related Impurities | <1.00% |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Granisetron Hydrocholride (CAS: 107007-99-8) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Russia, Kauslim Teb, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
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Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
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1-Methylindazole-3-Carboxylic Acid (CAS: 50890-83-0) yog ib qho nruab nrab ntawm Granisetron Hydrocholride (CAS: 107007-99-8).Granisetron Hydrochloride yog ib qho kev xaiv 5-HT3 receptor antagonist, uas muaj kev tiv thaiv zoo thiab kev kho mob ntawm xeev siab thiab ntuav los ntawm kev siv xov tooj cua, tshuaj kho mob thiab phais.Cov xwm txheej xws li kev kho hluav taws xob, tshuaj khomob thiab phais tuaj yeem ua rau kev tso tawm 5-HT los ntawm cov hnyuv chromaffin hlwb, thiab 5-HT tuaj yeem ua rau 5-HT3 receptor nyob rau hauv nruab nrab lossis vagus paj hlwb thiab ua rau ntuav reflex.Lub mechanism ntawm xeev siab thiab ntuav tswj los ntawm cov khoom no yog inhibition ntawm xeev siab thiab ntuav los ntawm antagonizing 5-HT3 receptors nyob rau hauv lub hauv paus chemoreceptor cheeb tsam thiab peripheral vagal terminals.Granisetron Hydrochloride muaj siab selectivity, tsis muaj extrapyramidal cov tshuaj tiv thaiv, ntau sedation thiab lwm yam kev phiv.