(1S,2S,3R,5S)-(+)-2,3-Pinadiol CAS 18680-27-8 ee ≥99.0% Purity ≥99.0% Bortezomib Intermediate High Purity
Muab Bortezomib Related Intermediates nrog High Purity
1S,2S,3R,5S)-(+)-2,3-Pinadiol CAS 18680-27-8
1R,2R,3S,5R)-(-)-2,3-Pinadiol CAS 22422-34-0
Bortezomib CAS 179324-69-7
| Tshuaj npe | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Synonyms | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]Heptane-2,3-diol |
| CAS Nr | 18680-27-8 ib |
| CAT Number | Qauv TSIS MUAJ: RF-CC290 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C10H18O2 |
| Molecular Luj | 170.25 Nws |
| Solubility | Chloroform, Toluene |
| Shipping Condition | Shipped nyob rau hauv ambient kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau Off-White Crystallized Powder |
| Melting Point | 56.0 ~ 59.0 ℃ |
| Poob rau ziab | ≤0.50% |
| Residue ntawm Ignition | ≤0.50% |
| Enantiomeric Tshaj | yog ≥ 99.0% |
| Purity / Analysis Method | ≥99.0% (GC) |
| Kev sib hloov tshwj xeeb [α]20/D | +8.5 ° txog +9.5 ° C = 6.5, Toluene |
| Infrared Spectrum | Ua raws |
| Test Standard | Enterprise Standard |
| Kev siv | Chiral compounds;Pharmaceutical Intermediates;Bortezomib Intermediate |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) nrog cov khoom zoo, dav siv hauv cov organic. synthesis, synthesis ntawm pharmaceutical intermediates thiab nplua tshuaj synthesis.
Shanghai Ruifu Chemical Co., Ltd. plays lub luag haujlwm tseem ceeb hauv chiral chemistry, lub tuam txhab tau cog lus rau kev tsim cov chiral compounds.Peb cov khoom tau qhuas los ntawm cov neeg siv khoom.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), yog ib qho tseem ceeb Chiral reagent siv nyob rau hauv lub synthesis ntawm homochiral α-hydroxyketones thiab nyob rau hauv kev daws teeb meem ntawm prolineboronate esters.Nws kuj yog ib qho tseem ceeb ua ntej rau chiral allyl boronate siv hauv kev npaj ntawm chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) yog ib qho nruab nrab ntawm Bortezomib (CAS 179324-69-7) hauv kev kho mob ntau yam Myeloma.Bortezomib, ib qho muaj zog ubiquitin proteasome (26S) inhibitor (Ki = 0.6 nM), tau tsim tawm hauv Asmeskas raws li kev kho mob rau ntau yam myeloma.Qhov no proteasome yog xav tau rau lub proteolytic degradation ntawm feem ntau ntawm cellular proteins thiab muaj nyob rau hauv tag nrho cov hlwb.Nws yog tsim nyog rau kev tswj cov txheej txheem inflammatory, kev tswj lub voj voog ntawm tes thiab kev qhia cov noob thiab yog lub hom phiaj tshiab hauv kev kho mob qog noj ntshav.
