2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Purity > 99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Chaw tsim khoom muab khoom, siab zoo thiab sib tw nqi
Tipiracil Hydrochloride (CAS: 183204-72-0) Muaj feem cuam tshuam
6-(Chloromethyl) uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
| Tshuaj npe | 2-Amino-1-Pyrroline Hydrochloride |
| Synonyms | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
| CAS Nr | 7544-75-4 ib |
| CAT Number | Qauv: RF-PI1838 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C4H8N2 · HCl |
| Molecular Luj | 120.58 Nws |
| Melting Point | 171.0 txog 175.0 ℃ |
| rhiab heev | Hygroscopic |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb hmoov | Dawb hmoov |
| Purity / Analysis Method | > 99.5% (HPLC) | 99.8% |
| Loj tshaj Ib Leeg Impurity | <0.50% | 0.09% |
| Cov ntsiab lus dej (KF) | <0.50% | 0.45% |
| Proton NMR Spectrum | Raws li tus qauv | Ua raws |
| Test Standard | Enterprise Standard | |
| Kev siv | Intermediate ntawm Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) yog ib qho heterocyclic organic compound, uas tuaj yeem siv los ua tshuaj nruab nrab.2-Amino-1-Pyrroline Hydrochloride yog ib qho nruab nrab ntawm Tipiracil Hydrochloride (CAS: 183204-72-0) hauv kev kho mob qog noj ntshav.Tipiracil Hydrochloride yog lub zog thiab kev sib tw inhibitor ntawm thymidine phosphorylase (TPase) nrog IC50 tus nqi ntawm 35 nM rau tib neeg placental TPase.Nws yog xaiv rau TPase tshaj lwm cov pyrimidine-metabolizing enzymes (IC50s => 1 mM rau UPase, OPRTase, TK, thiab DPDase).TPI inhibits phosphorolysis thiab degradation ntawm trifluorothymidine, cytotoxic nucleoside, hauv tib neeg lub mis thiab cov qog nqaij hlav qog noj ntshav.Kev tswj hwm qhov ncauj ntawm TPI (12.5-50 mg / kg) txhim kho kev tiv thaiv qog noj ntshav ntawm trifluorothymidine hauv nas AZ-521 mob qog noj ntshav xenograft qauv.Cov qauv uas muaj TPI tau siv rau kev kho mob qog nqaij hlav hauv plab hnyuv loj.
