2-Chloro-5-Iodobenzoic Acid CAS 19094-56-5 Empagliflozin Intermediate Assay ≥99.0% (HPLC)
Chaw tsim khoom, siab purity, coj mus muag ntau lawm
Lub npe tshuaj: 2-Chloro-5-Iodobenzoic Acid
CAS: 19094-56-5 Nr
Tshuaj npe | 2-Chloro-5-Iodobenzoic Acid |
CAS Nr | 19094-56-5 |
CAT Number | Qauv: RF-PI438 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C7H4ClIO2 |
Molecular Luj | 282.46 ib |
Solubility | Soluble hauv Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog daj daj Crystals |
Assay / Analysis Method | ≥99.0% (HPLC) |
Melting Point | 161.0 ~ 163.0 ℃ |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤ 0.20% |
Tag nrho cov impurities | ≤ 1.0% |
Hnyav Hlau | ≤ 20ppm |
Residual Solvent | Ethanol |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Empagliflozin (CAS: 864070-44-0) |
2-Chloro-5-Iodobenzoic Acid (CAS 19094-56-5) Synthetic Route
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
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2-Chloro-5-Iodobenzoic Acid (CAS: 19094-56-5) tuaj yeem siv los ua cov tshuaj nruab nrab hauv kev sib txuas ntawm Empagliflozin (CAS: 864070-44-0).Empagliflozin (lub npe lag luam Jardiance) yog ib qho inhibitor ntawm sodium glucose co-transporter-2 (SGLT-2), thiab ua rau cov piam thaj hauv cov ntshav tawm los ntawm ob lub raum thiab tshem tawm hauv cov zis.Thaum Lub Yim Hli 1, 2014, Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau lees paub cov tshuaj rau kev kho mob ntshav qab zib hom 2, txhawm rau txhim kho thiab tswj cov ntshav qabzib ntawm cov neeg laus.Empagliflozin yog thib peb SGLT-2 inhibiting tshuaj pom zoo los ntawm FDA.Lwm ob cov tshuaj SGLT-2 inhibitor, Canagliflozin thiab Dapagliflozin, uas yog Johnson Pharmaceuticals, AstraZeneca thiab Bristol-Myers Squibb feem, tau pom zoo los ntawm FDA thaum lub Kaum Ib Hlis 2013 thiab Lub Ib Hlis 2014 raws li.
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