2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5 Purity ≥98.0% Olaparib Intermediate Factory
High Purity, Kev lag luam ntau lawm
Olaparib thiab Related Intermediates:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1- (Cyclopropylcarbonyl) Piperazine Hydrochloride CAS 1021298-67-8
Tom ntej: 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Tshuaj npe | 2-Fluoro-5-Formylbenzonitrile |
| Synonyms | 3-Cyano-4-Fluorobenzaldehyde |
| CAS Nr | 218301-22-5 |
| CAT Number | Qauv: RF-PI451 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C8H4FNO |
| Molecular Luj | 149.12 Nws |
| Melting Point | 80.0 ~ 84.0 ℃ (lit.) |
| Solubility | Soluble hauv Methanol |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Yellow to Off-white Powder |
| Purity | ≥98.0% |
| Moisture (KF) | ≤0.50% |
| Tag nrho cov impurities | ≤ 2.0% |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate of Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
2-Fluoro-5-Formylbenzonitrile (CAS: 218301-22-5) yog siv rau hauv kev npaj ntawm heterocyclic compounds li PARP inhibitors rau kev kho mob.2-Fluoro-5-Formylbenzonitrile yog siv los ua ib qho nruab nrab ntawm Olaparib (CAS: 763113-22-0).Olaparib yog ib qho me me molecule inhibitor ntawm PARP1 / PARP2 (IC50: 5/1 nM) tab sis tsis zoo tiv thaiv PARP tankyrase-1 (IC50: 1.5 µM).Olaparib (AZD-2281, lub npe lag luam Lynparza) yog FDA pom zoo rau kev kho mob qog noj ntshav, tsim los ntawm KuDOS Pharmaceuticals thiab tom qab ntawd los ntawm AstraZeneca.Nws yog PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), ib qho enzyme koom nrog hauv DNA kho.Thaum Lub Kaum Ob Hlis 2014, olaparib tau pom zoo siv los ua ib tus neeg sawv cev los ntawm EMA thiab FDA.FDA pom zoo yog nyob rau hauv germline BRCA mutated (gBRCAm) mob cancer ntawm zes qe menyuam uas tau txais peb lossis ntau dua kab ua ntej ntawm kev kho mob.
