2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Purity ≥99.0% Pirfenidone Intermediate Factory
Chaw tsim khoom, siab purity, coj mus muag ntau lawm
Lub npe tshuaj: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5 Nr
Tshuaj npe | 2-Hydroxy-5-Methylpyridine |
Synonyms | 5-Methyl-2(1H)-Pyridinone;2-Hydroxy-5-Picoline;6-Hydroxy-3-Picoline;5-Methyl-2-Pyridinol |
CAS Nr | 1003-68-5 |
CAT Number | Qauv TSIS MUAJ: RF-PI549 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C6H7 Nr |
Molecular Luj | 109.13 Nws |
Melting Point | 183.0 ~ 187.0 ℃ (lit.) |
Solubility | Soluble hauv Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Off-White to Yellow Crystalline Powder |
Purity | ≥99.0% |
Moisture Content (KF) | ≤0.50% |
Residue ntawm Ignition | ≤0.50% |
Ib qho Impurity | ≤0.50% |
Tag nrho cov impurities | ≤ 1.00% |
Residual Solvents | |
N-Butanol | ≤ 0.30% |
Ethanol | ≤ 0.30% |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Pirfenidone (CAS: 53179-13-8) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) yog siv los ua tshuaj nruab nrab ntawm Pirfenidone (CAS: 53179-13-8).Pirfenidone (PFD) yog ib yam tshiab ntawm pyridine ketones uas muaj broad-spectrum anti-fibrotic nyhuv, muaj peev xwm tiv thaiv thiab thim rov qab tsim ntawm fibrosis thiab caws pliav.Nws nkag mus rau hauv kev ua lag luam hauv Shionogi, Nyiv xyoo 2008 thiab tau pom zoo los ntawm US Food and Drug Administration.Nws yog thawj cov tshuaj uas tau dhau los ntawm theem III kev sim tshuaj (nrog rau kev rov ua dua, randomized, thiab cov tshuaj placebo-tswj) uas tau qhia nws cov txiaj ntsig hauv kev kho mob idiopathic pulmonary fibrosis (IPF);Ntxiv mus, cov tshuaj muaj cov txiaj ntsig zoo hauv kev kho qee cov kab mob fibrotic xws li lub raum interstitial fibrosis thiab daim siab fibrosis.